High-precision flow velocity measurement in microfluidic chips using optical tweezers

Shouzhuang Zhao, Shangran Xie*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Accurate monitoring of flow velocity within a microfluidic chip is of critical importance. Existing devices for flow measurement in microfluidic chips lack the ability to provide detailed local flow velocity distribution or suffer from measurement errors. We present a novel optical tweezer velocimetry technique based on quadrant position detector with enhanced measurement accuracy. The impacts of laser trapping power on measurement range and the sensitivity of the technique are investigated. The velocity distribution at various depths inside the microfluidic chip under different flow conditions is resolved using the technique.

Original languageEnglish
Title of host publicationSecond International Academic Conference on Optics and Photonics, IACOP 2024
EditorsYang Yue
PublisherSPIE
ISBN (Electronic)9781510688810
DOIs
Publication statusPublished - 2025
Event2nd International Academic Conference on Optics and Photonics, IACOP 2024 - Haikou, China
Duration: 22 Nov 202424 Nov 2024

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume13541
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

Conference2nd International Academic Conference on Optics and Photonics, IACOP 2024
Country/TerritoryChina
CityHaikou
Period22/11/2424/11/24

Keywords

  • flow velocity measurement
  • microfluidic chip
  • Optical tweezer velocimetry

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