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Handheld miniature probe integrating diffuse optical tomography with photoacoustic imaging through a MEMS scanning mirror

  • Hao Yang
  • , Lei Xi
  • , Sean Samuelson
  • , Huikai Xie
  • , Lily Yang
  • , Huabei Jiang*
  • *Corresponding author for this work
  • University of Florida
  • Emory University

Research output: Contribution to journalArticlepeer-review

Abstract

We describe a novel dual-modality imaging approach that integrates diffuse optical tomography (DOT) and photoacoustic imaging (PAI) through a miniaturized handheld probe based on microelectromechanical systems (MEMS) scanning mirror. We validate this dual-modal DOT/PAI approach using extensive phantom experiments, and demonstrate its application for tumor imaging using tumor-bearing mice systematically injected with targeted contrast agents.

Original languageEnglish
Pages (from-to)427-432
Number of pages6
JournalBiomedical Optics Express
Volume4
Issue number3
DOIs
Publication statusPublished - 2013
Externally publishedYes

Keywords

  • (110.6960) Tomography
  • (170.0110) Imaging systems
  • (170.5120) Photoacoustic imaging

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