Handheld miniature probe integrating diffuse optical tomography with photoacoustic imaging through a MEMS scanning mirror

Hao Yang; Lei Xi; Sean Samuelson; Huikai Xie; Lily Yang; Huabei Jiang

doi:10.1364/BOE.4.000427

Handheld miniature probe integrating diffuse optical tomography with photoacoustic imaging through a MEMS scanning mirror

Hao Yang, Lei Xi, Sean Samuelson, Huikai Xie, Lily Yang, Huabei Jiang^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

45 Citations (Scopus)

Abstract

We describe a novel dual-modality imaging approach that integrates diffuse optical tomography (DOT) and photoacoustic imaging (PAI) through a miniaturized handheld probe based on microelectromechanical systems (MEMS) scanning mirror. We validate this dual-modal DOT/PAI approach using extensive phantom experiments, and demonstrate its application for tumor imaging using tumor-bearing mice systematically injected with targeted contrast agents.

Original language	English
Pages (from-to)	427-432
Number of pages	6
Journal	Biomedical Optics Express
Volume	4
Issue number	3
DOIs	https://doi.org/10.1364/BOE.4.000427
Publication status	Published - 2013
Externally published	Yes

Keywords

(110.6960) Tomography
(170.0110) Imaging systems
(170.5120) Photoacoustic imaging

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10.1364/BOE.4.000427

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abstract = "We describe a novel dual-modality imaging approach that integrates diffuse optical tomography (DOT) and photoacoustic imaging (PAI) through a miniaturized handheld probe based on microelectromechanical systems (MEMS) scanning mirror. We validate this dual-modal DOT/PAI approach using extensive phantom experiments, and demonstrate its application for tumor imaging using tumor-bearing mice systematically injected with targeted contrast agents.",

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AU - Yang, Hao

AU - Xi, Lei

AU - Samuelson, Sean

AU - Xie, Huikai

AU - Yang, Lily

AU - Jiang, Huabei

PY - 2013

Y1 - 2013

N2 - We describe a novel dual-modality imaging approach that integrates diffuse optical tomography (DOT) and photoacoustic imaging (PAI) through a miniaturized handheld probe based on microelectromechanical systems (MEMS) scanning mirror. We validate this dual-modal DOT/PAI approach using extensive phantom experiments, and demonstrate its application for tumor imaging using tumor-bearing mice systematically injected with targeted contrast agents.

AB - We describe a novel dual-modality imaging approach that integrates diffuse optical tomography (DOT) and photoacoustic imaging (PAI) through a miniaturized handheld probe based on microelectromechanical systems (MEMS) scanning mirror. We validate this dual-modal DOT/PAI approach using extensive phantom experiments, and demonstrate its application for tumor imaging using tumor-bearing mice systematically injected with targeted contrast agents.

KW - (110.6960) Tomography

KW - (170.0110) Imaging systems

KW - (170.5120) Photoacoustic imaging

UR - https://www.scopus.com/pages/publications/84874752155

U2 - 10.1364/BOE.4.000427

DO - 10.1364/BOE.4.000427

M3 - Article

AN - SCOPUS:84874752155

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JO - Biomedical Optics Express

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IS - 3

ER -

Handheld miniature probe integrating diffuse optical tomography with photoacoustic imaging through a MEMS scanning mirror

Abstract

Keywords

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