TY - GEN
T1 - Fluidic self-Assembly of multilayered Tubular microstructures by axis Translation inside Two-layered microfluidic devices
AU - Yue, Tao
AU - Nakajima, Masahiro
AU - Takeuchi, Masaru
AU - Huang, Qiang
AU - Fukuda, Toshio
N1 - Publisher Copyright:
© 2014 IEEE.
PY - 2014/9/22
Y1 - 2014/9/22
N2 - Microfluidic devices provide efficient approaches for building cellular Tubular structures for in vitro Tissue models in Tissue engineering. In This paper, we report a novel method of constructing Three-dimensional (3D) multilayered Tubular structures based on axis Translation of Two-dimensionally (2D) microstructures inside microfluidic devices. The on-chip fabrication of movable 2D microstructures embedding fibroblasts (NIH/3T3) based on Poly (ethylene glycol) Diacrylate (PEGDA) was reported. Novel Two-layered microfluidic devices were fabricated by Polydimethylsiloxane (PDMS), for conducting The fluidic self-Assembly of The 2D microstructures. The self-Assembly process was experimentally demonstrated. For improving The assembly results, a funneled structure and 3 micro grooves were added inside The microfluidic channel. Improved self-Assembly result of constructing a multilayered Tubular microstructure with higher efficiency was demonstrated.
AB - Microfluidic devices provide efficient approaches for building cellular Tubular structures for in vitro Tissue models in Tissue engineering. In This paper, we report a novel method of constructing Three-dimensional (3D) multilayered Tubular structures based on axis Translation of Two-dimensionally (2D) microstructures inside microfluidic devices. The on-chip fabrication of movable 2D microstructures embedding fibroblasts (NIH/3T3) based on Poly (ethylene glycol) Diacrylate (PEGDA) was reported. Novel Two-layered microfluidic devices were fabricated by Polydimethylsiloxane (PDMS), for conducting The fluidic self-Assembly of The 2D microstructures. The self-Assembly process was experimentally demonstrated. For improving The assembly results, a funneled structure and 3 micro grooves were added inside The microfluidic channel. Improved self-Assembly result of constructing a multilayered Tubular microstructure with higher efficiency was demonstrated.
UR - https://www.scopus.com/pages/publications/84929179613
U2 - 10.1109/ICRA.2014.6907717
DO - 10.1109/ICRA.2014.6907717
M3 - Conference contribution
AN - SCOPUS:84929179613
T3 - Proceedings - IEEE International Conference on Robotics and Automation
SP - 5836
EP - 5841
BT - Proceedings - IEEE International Conference on Robotics and Automation
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2014 IEEE International Conference on Robotics and Automation, ICRA 2014
Y2 - 31 May 2014 through 7 June 2014
ER -