Exploring Cardiopulmonary Interactions: A Novel Phase-Amplitude Coupling Method

Pengyan Tao, Chien Hung Yeh, Weifeng Li, Kaiwen Xu*, Wenbin Shi*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The cardiopulmonary coupling (CPC) involves complex interactions between the autonomic nervous system and respiratory control, affecting heart and respiratory rates. This study introduces a novel phase-amplitude coupling (PAC) method using the direct modulation index (dMI) for analyzing the bidirectional interactions between the heart rate variability and respiration of participants listening to classical music. The Empirical Mode Decomposition (EMD) was employed to decompose the RR intervals and the respiration signals, and the dMI-based PAC is then applied to the decomposed IMFs. The results demonstrate a notable enhancement in RESP-RR interactions during music exposure, indicating a stronger influence of respiratory patterns on heart rate during this relaxed state. Additionally, a pronounced cardiopulmonary coupling was observed in the low-frequency bands under conditions of listening to music. These findings highlight the complex, bidirectional interactions between breathing and heart rate. The dMI method emerges as a robust, noise-resistant analytical tool with promising implications for cardiovascular research and potential clinical applications.

Original languageEnglish
Title of host publication46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2024 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9798350371499
DOIs
Publication statusPublished - 2024
Event46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2024 - Orlando, United States
Duration: 15 Jul 202419 Jul 2024

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)1557-170X

Conference

Conference46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2024
Country/TerritoryUnited States
CityOrlando
Period15/07/2419/07/24

Keywords

  • Cardiopulmonary coupling
  • direct modulation index
  • phase-amplitude coupling

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