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Enhanced coherent anti-Stokes Raman scattering imaging using silica mircospheres

  • X. Huang
  • , X. N. He
  • , W. Xiong
  • , Y. Gao
  • , L. J. Jiang
  • , L. Liu
  • , Y. S. Zhou
  • , J. F. Silvain
  • , L. Jiang
  • , Y. F. Lu
  • University of Nebraska-Lincoln
  • Université de Bordeaux

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

A technique was developed to achieve enhanced coherent anti-Stokes Raman scattering (CARS) imaging using selfassembled silica microspheres. In this study, a layer of optically transparent silica microspheres was self-assembled onto polymer grating samples to enhance the CARS signals. The highest enhancement of 12.5 was achieved using 6.1-μmdiameter microspheres for C-H molecule vibration. Finite-difference time-domain (FDTD) algorithm under the perfectly matched layer boundary condition was used to simulate the enhancement using silica microspheres of different diameters.

Original languageEnglish
Title of host publicationNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XI
PublisherSPIE
ISBN (Print)9780819498670
DOIs
Publication statusPublished - 2014
EventNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XI - San Francisco, CA, United States
Duration: 3 Feb 20146 Feb 2014

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8954
ISSN (Print)1605-7422

Conference

ConferenceNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XI
Country/TerritoryUnited States
CitySan Francisco, CA
Period3/02/146/02/14

Keywords

  • Enhanced Coherent anti-Stokes Raman scattering
  • FDTD simulation
  • silica microspheres

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