Electron-Withdrawing Effects for Tailoring Oxidative-Stress-Mediated Coating in Marine Antifouling

Chao Wang, Rongrong Chen*, Wenbin Liu*, Jing Yu, Qi Liu, Jingyuan Liu, Jiahui Zhu, Cunguo Lin, Ying Li, Jun Wang*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Oxidative stress derived from excess reactive oxygen radicals (ROS) induces cellular damage, apoptosis, and necrosis, thus effective biofouling control by directly inhibiting primary membrane formation. However, the oxidative stress produced that does not rely on additional energy still is a challenge. Herein, an oxidative-stress-mediated marine antifouling polyurea coating is prepared leveraging the strong electron absorption effect of C═N. Given the structure of the urethane bond, the reversible reaction energy barrier of the dynamic urethane bond can be reduced, thereby enabling the urethane bond to be broken without the need for additional energy. The alkyl radical (R·) originating from the oxime-urethane bond can mediate the induction of oxidative stress in cells and microbial death, thus preserving exceptional antifouling properties and resisting most of the organism to adhere on the substrates. Notably, the coating indicates satisfactory antibacterial and antialgae performance and exhibits 8 months of marine field antifouling performance. In addition, the electron structure is investigated by theoretical calculation, and the interface behavior is investigated by molecular dynamics simulation. This work presents a pioneering example of the construction of oxidative-stress-mediated coating, which might be a judicious design strategy for an environmentally friendly marine antifouling coating.

Original languageEnglish
Pages (from-to)20438-20451
Number of pages14
JournalACS Applied Materials and Interfaces
Volume17
Issue number13
DOIs
Publication statusPublished - 2 Apr 2025
Externally publishedYes

Keywords

  • electron-withdrawing effects
  • marine antifouling
  • oxidative stress
  • polyurea
  • surface coating

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