TY - JOUR
T1 - Electron-Withdrawing Effects for Tailoring Oxidative-Stress-Mediated Coating in Marine Antifouling
AU - Wang, Chao
AU - Chen, Rongrong
AU - Liu, Wenbin
AU - Yu, Jing
AU - Liu, Qi
AU - Liu, Jingyuan
AU - Zhu, Jiahui
AU - Lin, Cunguo
AU - Li, Ying
AU - Wang, Jun
N1 - Publisher Copyright:
© 2025 American Chemical Society.
PY - 2025/4/2
Y1 - 2025/4/2
N2 - Oxidative stress derived from excess reactive oxygen radicals (ROS) induces cellular damage, apoptosis, and necrosis, thus effective biofouling control by directly inhibiting primary membrane formation. However, the oxidative stress produced that does not rely on additional energy still is a challenge. Herein, an oxidative-stress-mediated marine antifouling polyurea coating is prepared leveraging the strong electron absorption effect of C═N. Given the structure of the urethane bond, the reversible reaction energy barrier of the dynamic urethane bond can be reduced, thereby enabling the urethane bond to be broken without the need for additional energy. The alkyl radical (R·) originating from the oxime-urethane bond can mediate the induction of oxidative stress in cells and microbial death, thus preserving exceptional antifouling properties and resisting most of the organism to adhere on the substrates. Notably, the coating indicates satisfactory antibacterial and antialgae performance and exhibits 8 months of marine field antifouling performance. In addition, the electron structure is investigated by theoretical calculation, and the interface behavior is investigated by molecular dynamics simulation. This work presents a pioneering example of the construction of oxidative-stress-mediated coating, which might be a judicious design strategy for an environmentally friendly marine antifouling coating.
AB - Oxidative stress derived from excess reactive oxygen radicals (ROS) induces cellular damage, apoptosis, and necrosis, thus effective biofouling control by directly inhibiting primary membrane formation. However, the oxidative stress produced that does not rely on additional energy still is a challenge. Herein, an oxidative-stress-mediated marine antifouling polyurea coating is prepared leveraging the strong electron absorption effect of C═N. Given the structure of the urethane bond, the reversible reaction energy barrier of the dynamic urethane bond can be reduced, thereby enabling the urethane bond to be broken without the need for additional energy. The alkyl radical (R·) originating from the oxime-urethane bond can mediate the induction of oxidative stress in cells and microbial death, thus preserving exceptional antifouling properties and resisting most of the organism to adhere on the substrates. Notably, the coating indicates satisfactory antibacterial and antialgae performance and exhibits 8 months of marine field antifouling performance. In addition, the electron structure is investigated by theoretical calculation, and the interface behavior is investigated by molecular dynamics simulation. This work presents a pioneering example of the construction of oxidative-stress-mediated coating, which might be a judicious design strategy for an environmentally friendly marine antifouling coating.
KW - electron-withdrawing effects
KW - marine antifouling
KW - oxidative stress
KW - polyurea
KW - surface coating
UR - http://www.scopus.com/inward/record.url?scp=105001944939&partnerID=8YFLogxK
U2 - 10.1021/acsami.5c00106
DO - 10.1021/acsami.5c00106
M3 - Article
C2 - 40123055
AN - SCOPUS:105001944939
SN - 1944-8244
VL - 17
SP - 20438
EP - 20451
JO - ACS Applied Materials and Interfaces
JF - ACS Applied Materials and Interfaces
IS - 13
ER -