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Electromechanical Nanogenerators for Cell Modulation

  • Zhirong Liu
  • , Zhuo Wang
  • , Linlin Li*
  • *Corresponding author for this work
  • Chinese Academy of Sciences
  • University of Chinese Academy of Sciences

Research output: Contribution to journalReview articlepeer-review

Abstract

Bioelectricity is an indispensable part of organisms and plays a vital role in cell modulation and tissue/organ development. The development of convenient and bio-safe electrical stimulation equipment to simulate endogenous bioelectricity for cell function modulation is of great significance for its clinical transformation. In this review, we introduce the advantages of an electromechanical nanogenerator (EMNG) as a source of electrical stimulation in the biomedical field and systematically overview recent advances in EMNGs for cell modulation, mainly including cell adhesion, migration, proliferation and differentiation. Finally, we emphasize the significance of self-powered and biomimetic electrostimulation in cell modulation and discuss its challenges and future prospects in both basic research and clinical translation.

Original languageEnglish
Pages (from-to)110-132
Number of pages23
JournalNanoenergy Advances
Volume2
Issue number1
DOIs
Publication statusPublished - Mar 2022
Externally publishedYes

Keywords

  • cell modulation
  • electromechanical conversion
  • piezoelectric nanogenerator
  • self-powered
  • triboelectric nanogenerator

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