Electrochemical Cobalt-Catalyzed C-H Oxygenation at Room Temperature

Nicolas Sauermann; Tjark H. Meyer; Cong Tian; Lutz Ackermann

doi:10.1021/jacs.7b11025

Electrochemical Cobalt-Catalyzed C-H Oxygenation at Room Temperature

Nicolas Sauermann
, Tjark H. Meyer
, Cong Tian
, Lutz Ackermann^*

^*Corresponding author for this work

University of Göttingen

Research output: Contribution to journal › Article › peer-review

308 Citations (Scopus)

Abstract

Electrochemical cobalt-catalyzed C-H functionalizations were achieved in terms of C-H oxygenation under mild conditions at 23 °C. The robust electrochemical C-H functionalization was characterized by ample substrate scope, whereas mechanistic studies provided support for a facile C-H cleavage. The electrochemical cobalt-catalyzed C-H oxygenation proved viable on arenes and alkenes with excellent levels of positional and diastereo-selectivity, avoiding the use of stoichiometric silver(I) oxidants under ambient conditions.

Original language	English
Pages (from-to)	18452-18455
Number of pages	4
Journal	Journal of the American Chemical Society
Volume	139
Issue number	51
DOIs	https://doi.org/10.1021/jacs.7b11025
Publication status	Published - 27 Dec 2017
Externally published	Yes

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title = "Electrochemical Cobalt-Catalyzed C-H Oxygenation at Room Temperature",

abstract = "Electrochemical cobalt-catalyzed C-H functionalizations were achieved in terms of C-H oxygenation under mild conditions at 23 °C. The robust electrochemical C-H functionalization was characterized by ample substrate scope, whereas mechanistic studies provided support for a facile C-H cleavage. The electrochemical cobalt-catalyzed C-H oxygenation proved viable on arenes and alkenes with excellent levels of positional and diastereo-selectivity, avoiding the use of stoichiometric silver(I) oxidants under ambient conditions.",

author = "Nicolas Sauermann and Meyer, \{Tjark H.\} and Cong Tian and Lutz Ackermann",

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AU - Sauermann, Nicolas

AU - Meyer, Tjark H.

AU - Tian, Cong

AU - Ackermann, Lutz

PY - 2017/12/27

Y1 - 2017/12/27

N2 - Electrochemical cobalt-catalyzed C-H functionalizations were achieved in terms of C-H oxygenation under mild conditions at 23 °C. The robust electrochemical C-H functionalization was characterized by ample substrate scope, whereas mechanistic studies provided support for a facile C-H cleavage. The electrochemical cobalt-catalyzed C-H oxygenation proved viable on arenes and alkenes with excellent levels of positional and diastereo-selectivity, avoiding the use of stoichiometric silver(I) oxidants under ambient conditions.

AB - Electrochemical cobalt-catalyzed C-H functionalizations were achieved in terms of C-H oxygenation under mild conditions at 23 °C. The robust electrochemical C-H functionalization was characterized by ample substrate scope, whereas mechanistic studies provided support for a facile C-H cleavage. The electrochemical cobalt-catalyzed C-H oxygenation proved viable on arenes and alkenes with excellent levels of positional and diastereo-selectivity, avoiding the use of stoichiometric silver(I) oxidants under ambient conditions.

UR - https://www.scopus.com/pages/publications/85039928378

U2 - 10.1021/jacs.7b11025

DO - 10.1021/jacs.7b11025

M3 - Article

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AN - SCOPUS:85039928378

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JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 51

ER -

Electrochemical Cobalt-Catalyzed C-H Oxygenation at Room Temperature

Abstract

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