Elastic X-ray image registration based on mutual information and thin-plate spline

A novel technique based on mutual information and thin-plate spline is proposed for the registration of coronary angiography images. This method not only resolves the uncertain problem of the calculating block size of traditional template matching method, but also removes the bad influence of the starting point of the optimization and insures to find global minimum. Experimental results show that the proposed method is able to achieve sub-pixel registration precision.