TY - JOUR
T1 - Efficient synthesis of taurine and structurally diverse substituted taurines from aziridines
AU - Hu, Libo
AU - Zhu, Hui
AU - Du, Da Ming
AU - Xu, Jiaxi
PY - 2007/6/8
Y1 - 2007/6/8
N2 - (Chemical Equation Presented) Taurine and substituted taurines were synthesized efficiently from aziridines via ring-opening reaction with thioacetic acid, oxidation with performic acid, and hydrolysis in hydrochloric acid. The current method shows more benefit in purification and efficiency in the preparation of taurine and structurally diverse 2-substituted, 2,2-disubstituted, and 1,2-, 2,2-, and 2,N-alkylene taurines.
AB - (Chemical Equation Presented) Taurine and substituted taurines were synthesized efficiently from aziridines via ring-opening reaction with thioacetic acid, oxidation with performic acid, and hydrolysis in hydrochloric acid. The current method shows more benefit in purification and efficiency in the preparation of taurine and structurally diverse 2-substituted, 2,2-disubstituted, and 1,2-, 2,2-, and 2,N-alkylene taurines.
UR - https://www.scopus.com/pages/publications/34250166116
U2 - 10.1021/jo070470c
DO - 10.1021/jo070470c
M3 - Article
C2 - 17497929
AN - SCOPUS:34250166116
SN - 0022-3263
VL - 72
SP - 4543
EP - 4546
JO - Journal of Organic Chemistry
JF - Journal of Organic Chemistry
IS - 12
ER -