Direct synthesis of hierarchical monolithic silica for high performance liquid chromatography

Hua Zhong; Guiru Zhu; Peiyuan Wang; Jian Liu; Jie Yang; Qihua Yang

doi:10.1016/j.chroma.2008.03.045

Direct synthesis of hierarchical monolithic silica for high performance liquid chromatography

Hua Zhong
, Guiru Zhu
, Peiyuan Wang
, Jian Liu
, Jie Yang
, Qihua Yang^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

Abstract

The silica-based monolith exhibiting a hierarchical bimodal porous structure has been directly synthesized via lytropic mesophase. The hydrolysis and condensation of tetramethoxysilane (TMOS) in the presence of poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (P123) and acetic acid results in silica monolith with MSU-type mesoporous structure embedded in the skeleton of the interconnected macropore. The silica monolith with bimodal porous structure can separate benzene and phenol with high flow rate and low back-pressure. Moreover, the chromatographic property of C₁₈-grafted silica monolith is investigated in the separation of aromatic molecules. Our primary result shows that the silica monolith with interconnected macropore and MSU-type mesopore is a promising packing material as stationary phase for high performance liquid chromatography.

Original language	English
Pages (from-to)	232-240
Number of pages	9
Journal	Journal of Chromatography A
Volume	1190
Issue number	1-2
DOIs	https://doi.org/10.1016/j.chroma.2008.03.045
Publication status	Published - 9 May 2008
Externally published	Yes

Keywords

Bimodal porous structure
High performance liquid chromatography
Macroporous
Silica monolith

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10.1016/j.chroma.2008.03.045

Cite this

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title = "Direct synthesis of hierarchical monolithic silica for high performance liquid chromatography",

abstract = "The silica-based monolith exhibiting a hierarchical bimodal porous structure has been directly synthesized via lytropic mesophase. The hydrolysis and condensation of tetramethoxysilane (TMOS) in the presence of poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (P123) and acetic acid results in silica monolith with MSU-type mesoporous structure embedded in the skeleton of the interconnected macropore. The silica monolith with bimodal porous structure can separate benzene and phenol with high flow rate and low back-pressure. Moreover, the chromatographic property of C18-grafted silica monolith is investigated in the separation of aromatic molecules. Our primary result shows that the silica monolith with interconnected macropore and MSU-type mesopore is a promising packing material as stationary phase for high performance liquid chromatography.",

keywords = "Bimodal porous structure, High performance liquid chromatography, Macroporous, Silica monolith",

author = "Hua Zhong and Guiru Zhu and Peiyuan Wang and Jian Liu and Jie Yang and Qihua Yang",

year = "2008",

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day = "9",

doi = "10.1016/j.chroma.2008.03.045",

language = "English",

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journal = "Journal of Chromatography A",

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TY - JOUR

T1 - Direct synthesis of hierarchical monolithic silica for high performance liquid chromatography

AU - Zhong, Hua

AU - Zhu, Guiru

AU - Wang, Peiyuan

AU - Liu, Jian

AU - Yang, Jie

AU - Yang, Qihua

PY - 2008/5/9

Y1 - 2008/5/9

N2 - The silica-based monolith exhibiting a hierarchical bimodal porous structure has been directly synthesized via lytropic mesophase. The hydrolysis and condensation of tetramethoxysilane (TMOS) in the presence of poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (P123) and acetic acid results in silica monolith with MSU-type mesoporous structure embedded in the skeleton of the interconnected macropore. The silica monolith with bimodal porous structure can separate benzene and phenol with high flow rate and low back-pressure. Moreover, the chromatographic property of C18-grafted silica monolith is investigated in the separation of aromatic molecules. Our primary result shows that the silica monolith with interconnected macropore and MSU-type mesopore is a promising packing material as stationary phase for high performance liquid chromatography.

AB - The silica-based monolith exhibiting a hierarchical bimodal porous structure has been directly synthesized via lytropic mesophase. The hydrolysis and condensation of tetramethoxysilane (TMOS) in the presence of poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (P123) and acetic acid results in silica monolith with MSU-type mesoporous structure embedded in the skeleton of the interconnected macropore. The silica monolith with bimodal porous structure can separate benzene and phenol with high flow rate and low back-pressure. Moreover, the chromatographic property of C18-grafted silica monolith is investigated in the separation of aromatic molecules. Our primary result shows that the silica monolith with interconnected macropore and MSU-type mesopore is a promising packing material as stationary phase for high performance liquid chromatography.

KW - Bimodal porous structure

KW - High performance liquid chromatography

KW - Macroporous

KW - Silica monolith

UR - https://www.scopus.com/pages/publications/42049107531

U2 - 10.1016/j.chroma.2008.03.045

DO - 10.1016/j.chroma.2008.03.045

M3 - Article

C2 - 18395733

AN - SCOPUS:42049107531

SN - 0021-9673

VL - 1190

SP - 232

EP - 240

JO - Journal of Chromatography A

JF - Journal of Chromatography A

IS - 1-2

ER -

Direct synthesis of hierarchical monolithic silica for high performance liquid chromatography

Abstract

Keywords

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