Development of experimental setup to create novel mental disorder model rats using small mobile robot

Hiroyuki Ishii; Qing Shi; Yuichi Masuda; Syunsuke Miyagishima; Syogo Fumino; Atsuo Takanishi; Satoshi Okabayashi; Naritoshi Iida; Hiroshi Kimura; Yu Tahara; Akiko Hirao; Shigenobu Shibata

doi:10.1109/IROS.2010.5649764

Development of experimental setup to create novel mental disorder model rats using small mobile robot

Hiroyuki Ishii^*
, Qing Shi
, Yuichi Masuda
, Syunsuke Miyagishima
, Syogo Fumino
, Atsuo Takanishi
, Satoshi Okabayashi
, Naritoshi Iida
, Hiroshi Kimura
, Yu Tahara
, Akiko Hirao
, Shigenobu Shibata

^*Corresponding author for this work

School of Mechatronical Engineering

Waseda University
Faculty of Science and Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

12 Citations (Scopus)

Abstract

The number of patients with mental disorders is increasing in advanced countries. Many researchers are working to develop mental disorder model animals that contribute to development of new psychotropic drugs. However, we have some doubts about conventional mental disorder models. Therefore, the purpose of this study is to develop an experimental setup to create novel mental disorder model animals. We then developed a small mobile robot and a control system for the robot. Using them, we performed an experiment to develop a mental disorder model rat. In the experiment, we succeeded in developing a new depression model rat and also high activity model rat. These disorder models must be useful in the screening of new psychotropic drugs. In addition, the methodology we developed in this research will contribute to clarifying mechanisms of mental disorders.

Original language	English
Title of host publication	IEEE/RSJ 2010 International Conference on Intelligent Robots and Systems, IROS 2010 - Conference Proceedings
Pages	3905-3910
Number of pages	6
DOIs	https://doi.org/10.1109/IROS.2010.5649764
Publication status	Published - 2010
Event	23rd IEEE/RSJ 2010 International Conference on Intelligent Robots and Systems, IROS 2010 - Taipei, Taiwan, Province of China Duration: 18 Oct 2010 → 22 Oct 2010

Publication series

Name	IEEE/RSJ 2010 International Conference on Intelligent Robots and Systems, IROS 2010 - Conference Proceedings

Conference

Conference	23rd IEEE/RSJ 2010 International Conference on Intelligent Robots and Systems, IROS 2010
Country/Territory	Taiwan, Province of China
City	Taipei
Period	18/10/10 → 22/10/10

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1109/IROS.2010.5649764

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Ishii, H., Shi, Q., Masuda, Y., Miyagishima, S., Fumino, S., Takanishi, A., Okabayashi, S., Iida, N., Kimura, H., Tahara, Y., Hirao, A., & Shibata, S. (2010). Development of experimental setup to create novel mental disorder model rats using small mobile robot. In IEEE/RSJ 2010 International Conference on Intelligent Robots and Systems, IROS 2010 - Conference Proceedings (pp. 3905-3910). Article 5649764 (IEEE/RSJ 2010 International Conference on Intelligent Robots and Systems, IROS 2010 - Conference Proceedings). https://doi.org/10.1109/IROS.2010.5649764

Ishii, Hiroyuki ; Shi, Qing ; Masuda, Yuichi et al. / Development of experimental setup to create novel mental disorder model rats using small mobile robot. IEEE/RSJ 2010 International Conference on Intelligent Robots and Systems, IROS 2010 - Conference Proceedings. 2010. pp. 3905-3910 (IEEE/RSJ 2010 International Conference on Intelligent Robots and Systems, IROS 2010 - Conference Proceedings).

@inproceedings{4b01853cd33147f69ffa883b057ddd20,

title = "Development of experimental setup to create novel mental disorder model rats using small mobile robot",

abstract = "The number of patients with mental disorders is increasing in advanced countries. Many researchers are working to develop mental disorder model animals that contribute to development of new psychotropic drugs. However, we have some doubts about conventional mental disorder models. Therefore, the purpose of this study is to develop an experimental setup to create novel mental disorder model animals. We then developed a small mobile robot and a control system for the robot. Using them, we performed an experiment to develop a mental disorder model rat. In the experiment, we succeeded in developing a new depression model rat and also high activity model rat. These disorder models must be useful in the screening of new psychotropic drugs. In addition, the methodology we developed in this research will contribute to clarifying mechanisms of mental disorders.",

author = "Hiroyuki Ishii and Qing Shi and Yuichi Masuda and Syunsuke Miyagishima and Syogo Fumino and Atsuo Takanishi and Satoshi Okabayashi and Naritoshi Iida and Hiroshi Kimura and Yu Tahara and Akiko Hirao and Shigenobu Shibata",

year = "2010",

doi = "10.1109/IROS.2010.5649764",

language = "English",

isbn = "9781424466757",

series = "IEEE/RSJ 2010 International Conference on Intelligent Robots and Systems, IROS 2010 - Conference Proceedings",

pages = "3905--3910",

booktitle = "IEEE/RSJ 2010 International Conference on Intelligent Robots and Systems, IROS 2010 - Conference Proceedings",

note = "23rd IEEE/RSJ 2010 International Conference on Intelligent Robots and Systems, IROS 2010 ; Conference date: 18-10-2010 Through 22-10-2010",

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Ishii, H, Shi, Q, Masuda, Y, Miyagishima, S, Fumino, S, Takanishi, A, Okabayashi, S, Iida, N, Kimura, H, Tahara, Y, Hirao, A & Shibata, S 2010, Development of experimental setup to create novel mental disorder model rats using small mobile robot. in IEEE/RSJ 2010 International Conference on Intelligent Robots and Systems, IROS 2010 - Conference Proceedings., 5649764, IEEE/RSJ 2010 International Conference on Intelligent Robots and Systems, IROS 2010 - Conference Proceedings, pp. 3905-3910, 23rd IEEE/RSJ 2010 International Conference on Intelligent Robots and Systems, IROS 2010, Taipei, Taiwan, Province of China, 18/10/10. https://doi.org/10.1109/IROS.2010.5649764

Development of experimental setup to create novel mental disorder model rats using small mobile robot. / Ishii, Hiroyuki; Shi, Qing; Masuda, Yuichi et al.
IEEE/RSJ 2010 International Conference on Intelligent Robots and Systems, IROS 2010 - Conference Proceedings. 2010. p. 3905-3910 5649764 (IEEE/RSJ 2010 International Conference on Intelligent Robots and Systems, IROS 2010 - Conference Proceedings).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Ishii, Hiroyuki

AU - Shi, Qing

AU - Masuda, Yuichi

AU - Miyagishima, Syunsuke

AU - Fumino, Syogo

AU - Takanishi, Atsuo

AU - Okabayashi, Satoshi

AU - Iida, Naritoshi

AU - Kimura, Hiroshi

AU - Tahara, Yu

AU - Hirao, Akiko

AU - Shibata, Shigenobu

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AB - The number of patients with mental disorders is increasing in advanced countries. Many researchers are working to develop mental disorder model animals that contribute to development of new psychotropic drugs. However, we have some doubts about conventional mental disorder models. Therefore, the purpose of this study is to develop an experimental setup to create novel mental disorder model animals. We then developed a small mobile robot and a control system for the robot. Using them, we performed an experiment to develop a mental disorder model rat. In the experiment, we succeeded in developing a new depression model rat and also high activity model rat. These disorder models must be useful in the screening of new psychotropic drugs. In addition, the methodology we developed in this research will contribute to clarifying mechanisms of mental disorders.

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BT - IEEE/RSJ 2010 International Conference on Intelligent Robots and Systems, IROS 2010 - Conference Proceedings

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Ishii H, Shi Q, Masuda Y, Miyagishima S, Fumino S, Takanishi A et al. Development of experimental setup to create novel mental disorder model rats using small mobile robot. In IEEE/RSJ 2010 International Conference on Intelligent Robots and Systems, IROS 2010 - Conference Proceedings. 2010. p. 3905-3910. 5649764. (IEEE/RSJ 2010 International Conference on Intelligent Robots and Systems, IROS 2010 - Conference Proceedings). doi: 10.1109/IROS.2010.5649764

Development of experimental setup to create novel mental disorder model rats using small mobile robot

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