Detection of pathological myopia by PAMELA with texture-based features through an SVM approach

Jiang Liu*, Damon W.K. Wong, Joo Hwee Lim, Ngan Meng Tan, Zhuo Zhang, Huiqi Li, Fengshou Yin, Benghai Lee, Seang Mei Saw, Louis Tong, Tien Yin Wong

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

44 Citations (Scopus)

Abstract

Pathological myopia is the seventh leading cause of blindness worldwide. Current methods for the detection of pathological myopia are manual and subjective. We have developed a system known as PAMELA (Pathological Myopia Detection Through Peripapillary Atrophy) to automatically assess a retinal fundus image for pathological myopia. This paper focuses on the texture analysis component of PAMELA which uses texture features, clinical image context and support vector machine-based classification to detect the presence of pathological myopia in a retinal fundus image. Results on a test image set from the Singapore Eye Research Institute show an accuracy of 87.5% and a sensitivity and specificity of 0.85 and 0.90 respectively. The results show good promise for PAMELA to be developed as an automatic tool for pathological myopia detection.

Original languageEnglish
Pages (from-to)1-11
Number of pages11
JournalJournal of Healthcare Engineering
Volume1
Issue number1
DOIs
Publication statusPublished - Mar 2010
Externally publishedYes

Keywords

  • Computer aided detection
  • Pathological myopia
  • Peripapillary atrophy

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