Design strategies for lab-on-a-molecule probes and orthogonal sensing

Kun Chen; Qinghai Shu; Michael Schmittel

doi:10.1039/c4cs00263f

Design strategies for lab-on-a-molecule probes and orthogonal sensing

Kun Chen
, Qinghai Shu
, Michael Schmittel^*

^*Corresponding author for this work

School of Material Science and Engineering

University of Siegen

Research output: Contribution to journal › Review article › peer-review

146 Citations (Scopus)

Abstract

This review highlights the currently exploited working concepts of lab-on-a-molecule probes, with a particular focus on what is required for multianalyte detection and quantification in competitive assays. Both, chemosensor and chemodosimeter approaches are considered. The multifaceted design strategies and the orthogonal protocols are evaluated in order to identify and categorise the successful conceptions and to single out unknown territory and challenges for future work.

Original language	English
Pages (from-to)	136-160
Number of pages	25
Journal	Chemical Society Reviews
Volume	44
Issue number	1
DOIs	https://doi.org/10.1039/c4cs00263f
Publication status	Published - 7 Jan 2015

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title = "Design strategies for lab-on-a-molecule probes and orthogonal sensing",

abstract = "This review highlights the currently exploited working concepts of lab-on-a-molecule probes, with a particular focus on what is required for multianalyte detection and quantification in competitive assays. Both, chemosensor and chemodosimeter approaches are considered. The multifaceted design strategies and the orthogonal protocols are evaluated in order to identify and categorise the successful conceptions and to single out unknown territory and challenges for future work.",

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AB - This review highlights the currently exploited working concepts of lab-on-a-molecule probes, with a particular focus on what is required for multianalyte detection and quantification in competitive assays. Both, chemosensor and chemodosimeter approaches are considered. The multifaceted design strategies and the orthogonal protocols are evaluated in order to identify and categorise the successful conceptions and to single out unknown territory and challenges for future work.

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Design strategies for lab-on-a-molecule probes and orthogonal sensing

Abstract

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