Cytotoxicity and antibacterial activity of chitosan-organic rectorite intercalated nanofibrous mats

Jing Du; Xueyong Li; Chen Yang; Wei Li; Weijuan Huang; Rong Huang; Xue Zhou; Hongbing Deng

doi:10.2174/157341313805117785

Cytotoxicity and antibacterial activity of chitosan-organic rectorite intercalated nanofibrous mats

Jing Du, Xueyong Li, Chen Yang, Wei Li, Weijuan Huang, Rong Huang, Xue Zhou^*, Hongbing Deng

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

The chitosan (CS)-organic rectorite (OREC) composites are prepared with the method of solution intercalation. Electrospun nanofibrous mats are made from intercalated CS-OREC composites at different mass ratios. The properties and structure of intercalated CS-OREC can be verified by small angle X-ray diffraction (SAXRD) and transmission electron microscopy (TEM) micrographs. Energy dispersive X-ray (EDX) spectroscopy and fourier transform infrared (FT-IR) spectra reveal that OREC presents in the composite nanofibrous mats. The MTT assay indicates that the cytotoxicity of the intercalated CS-OREC nanofibrous mats is low. Besides, the content of OREC in nanofibrous mats has a significant influence on the viability of cells. Antibacterial test confirms that OREC can increase the inhibition rate of the nanofibrous mats against Escherichia coli.

Original language	English
Pages (from-to)	8-13
Number of pages	6
Journal	Current Nanoscience
Volume	9
Issue number	1
DOIs	https://doi.org/10.2174/157341313805117785
Publication status	Published - 2013
Externally published	Yes

Keywords

Antibacterial activity
Bacterial activity
Chitosan
Cytotoxicity
Electrospinning
Intercalation
Organic rectorite

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title = "Cytotoxicity and antibacterial activity of chitosan-organic rectorite intercalated nanofibrous mats",

abstract = "The chitosan (CS)-organic rectorite (OREC) composites are prepared with the method of solution intercalation. Electrospun nanofibrous mats are made from intercalated CS-OREC composites at different mass ratios. The properties and structure of intercalated CS-OREC can be verified by small angle X-ray diffraction (SAXRD) and transmission electron microscopy (TEM) micrographs. Energy dispersive X-ray (EDX) spectroscopy and fourier transform infrared (FT-IR) spectra reveal that OREC presents in the composite nanofibrous mats. The MTT assay indicates that the cytotoxicity of the intercalated CS-OREC nanofibrous mats is low. Besides, the content of OREC in nanofibrous mats has a significant influence on the viability of cells. Antibacterial test confirms that OREC can increase the inhibition rate of the nanofibrous mats against Escherichia coli.",

keywords = "Antibacterial activity, Bacterial activity, Chitosan, Cytotoxicity, Electrospinning, Intercalation, Organic rectorite",

author = "Jing Du and Xueyong Li and Chen Yang and Wei Li and Weijuan Huang and Rong Huang and Xue Zhou and Hongbing Deng",

year = "2013",

doi = "10.2174/157341313805117785",

language = "English",

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T1 - Cytotoxicity and antibacterial activity of chitosan-organic rectorite intercalated nanofibrous mats

AU - Du, Jing

AU - Li, Xueyong

AU - Yang, Chen

AU - Li, Wei

AU - Huang, Weijuan

AU - Huang, Rong

AU - Zhou, Xue

AU - Deng, Hongbing

PY - 2013

Y1 - 2013

N2 - The chitosan (CS)-organic rectorite (OREC) composites are prepared with the method of solution intercalation. Electrospun nanofibrous mats are made from intercalated CS-OREC composites at different mass ratios. The properties and structure of intercalated CS-OREC can be verified by small angle X-ray diffraction (SAXRD) and transmission electron microscopy (TEM) micrographs. Energy dispersive X-ray (EDX) spectroscopy and fourier transform infrared (FT-IR) spectra reveal that OREC presents in the composite nanofibrous mats. The MTT assay indicates that the cytotoxicity of the intercalated CS-OREC nanofibrous mats is low. Besides, the content of OREC in nanofibrous mats has a significant influence on the viability of cells. Antibacterial test confirms that OREC can increase the inhibition rate of the nanofibrous mats against Escherichia coli.

AB - The chitosan (CS)-organic rectorite (OREC) composites are prepared with the method of solution intercalation. Electrospun nanofibrous mats are made from intercalated CS-OREC composites at different mass ratios. The properties and structure of intercalated CS-OREC can be verified by small angle X-ray diffraction (SAXRD) and transmission electron microscopy (TEM) micrographs. Energy dispersive X-ray (EDX) spectroscopy and fourier transform infrared (FT-IR) spectra reveal that OREC presents in the composite nanofibrous mats. The MTT assay indicates that the cytotoxicity of the intercalated CS-OREC nanofibrous mats is low. Besides, the content of OREC in nanofibrous mats has a significant influence on the viability of cells. Antibacterial test confirms that OREC can increase the inhibition rate of the nanofibrous mats against Escherichia coli.

KW - Antibacterial activity

KW - Bacterial activity

KW - Chitosan

KW - Cytotoxicity

KW - Electrospinning

KW - Intercalation

KW - Organic rectorite

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DO - 10.2174/157341313805117785

M3 - Article

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SN - 1573-4137

VL - 9

SP - 8

EP - 13

JO - Current Nanoscience

JF - Current Nanoscience

IS - 1

ER -

Cytotoxicity and antibacterial activity of chitosan-organic rectorite intercalated nanofibrous mats

Abstract

Keywords

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