Contactless Droplet Mixing Based on Acoustic Tweezer

Droplet mixing research provides critical technical support for developing efficient and controllable complex chemical reaction systems. However, traditional methods and platforms pose inherent risks including cross-contamination and low energy conversion efficiency. Emerging alternative approaches, such as microfluidic chips, often entail complex fabrication processes and operational challenges. To address these limitations, this study proposes a non-contact droplet mixing platform. By applying a vortex acoustic field to droplets on a glass substrate, this system achieves stable droplet capture, precise manipulation, and rapid mixing. The platform significantly reduces contamination risks, minimizes reagent consumption, and enhances energy conversion efficiency, while featuring straightforward fabrication and operational simplicity. Experimental results demonstrate the system's efficacy in accelerating microvolume droplet mixing, offering a practical solution for advanced chemical research.