@inproceedings{1c3ef7a30a544bba89ac0743fec03d56,
title = "Construction of vascular-like microtubes via fluidic axis-translation self-assembly based on multiple hydrogels",
abstract = "Cellular vascular-like microtubes occupy an important position in tissue engineering for building in vitro tissue models. In this paper, we report a method of constructing three-dimensional (3D) multilayered vascular-like microtubes based on fluidic axis-translation self-assembly of two-dimensional (2D) microstructures inside microfluidic devices. The on-chip fabrication of cell (fibroblasts NIH/3T3) embedded 2D microstructures based on Poly (ethylene glycol) Diacrylate (PEGDA) and biodegradable material Gelatin Methacrylate (GelMa) were reported. A multilayered Polydimethylsiloxane (PDMS) microfluidic device was fabricated for conducting the fluidic self-assembly of 2D microstructures. The fluidic axis-translation self-assembly process was experimentally demonstrated. Multiple hydrogels embedded microtube was constructed. The fabrication of GelMa microstructures was demonstrated. The degradability of cell embedded GelMa microstructures was evaluated by long-term observation, and it shows the great potential of GelMa to be used for constructing cellular vascular-like microtubes.",
author = "Tao Yue and Masahiro Nakajima and Masaru Takeuchi and Qiang Huang and Toshio Fukuda",
note = "Publisher Copyright: {\textcopyright} 2014 IEEE.; 2014 IEEE/RSJ International Conference on Intelligent Robots and Systems, IROS 2014 ; Conference date: 14-09-2014 Through 18-09-2014",
year = "2014",
month = oct,
day = "31",
doi = "10.1109/IROS.2014.6942651",
language = "English",
series = "IEEE International Conference on Intelligent Robots and Systems",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "803--808",
booktitle = "IROS 2014 Conference Digest - IEEE/RSJ International Conference on Intelligent Robots and Systems",
address = "United States",
}