Abstract
In summary, this study indicates that functional DCs can be differentiated from MDR K562/A02 cells and effectively generate a P-gp-specific antileukemic immune response. If a DC based vaccine loaded with P-gp or transferred by mdr1 gene is designed, it maybe provide a novel and promising immunotherapeutic strategy to overcome MDR leukemia in the future.
| Original language | English |
|---|---|
| Pages (from-to) | 595-597 |
| Number of pages | 3 |
| Journal | Chinese Medical Journal |
| Volume | 118 |
| Issue number | 7 |
| Publication status | Published - 5 Apr 2005 |
| Externally published | Yes |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Dendritic cells
- Immunity
- Leukemia
- Multidrug resistance
- P-glycoprotein
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