Cell sheets fabrication with mimicking morphology of liver lobule tissue by electrodeposition

Minmin Lu; Zeyang Liu; Masahiro Nakajima; Masaru Takeuchi; Yasuhisa Hasegawa; Toshio Fukuda; Qiang Huang

doi:10.1109/MHS.2016.7824181

Cell sheets fabrication with mimicking morphology of liver lobule tissue by electrodeposition

Minmin Lu
, Zeyang Liu
, Masahiro Nakajima
, Masaru Takeuchi
, Yasuhisa Hasegawa
, Toshio Fukuda
, Qiang Huang

School of Mechatronical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

In this paper, a novel approach is presented to obtain the cell sheets with mimicking the morphology of liver lobule tissue by electrodeposition method. We would take some steps to gain the sheets. It includes: 1) fabricate microelectrode which coated pattern onto fluorine-doped tin oxide (FTO) glass based on photolithography technique. 2) electrodeposition experiment which embedded with RLC-18 (rat liver) cells. 3) detach the sheet from the microelectrode by shaking it. 4) assemble 3D tissue structure. In the result, precise pattern in the sheet could be kept and the viability of the cells could be maintained. We also checked the height of the sheet. We believe the use of cell sheets by electrodeposition method is great potential in fabricating 3D cell structures.

Original language	English
Title of host publication	2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)	9781509027842
DOIs	https://doi.org/10.1109/MHS.2016.7824181
Publication status	Published - 18 Jan 2017
Event	27th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016 - Nagoya, Japan Duration: 28 Nov 2016 → 30 Nov 2016

Publication series

Name	2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016

Conference

Conference	27th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016
Country/Territory	Japan
City	Nagoya
Period	28/11/16 → 30/11/16

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1109/MHS.2016.7824181

Cite this

Lu, M., Liu, Z., Nakajima, M., Takeuchi, M., Hasegawa, Y., Fukuda, T., & Huang, Q. (2017). Cell sheets fabrication with mimicking morphology of liver lobule tissue by electrodeposition. In 2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016 Article 7824181 (2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MHS.2016.7824181

Lu, Minmin ; Liu, Zeyang ; Nakajima, Masahiro et al. / Cell sheets fabrication with mimicking morphology of liver lobule tissue by electrodeposition. 2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016. Institute of Electrical and Electronics Engineers Inc., 2017. (2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016).

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title = "Cell sheets fabrication with mimicking morphology of liver lobule tissue by electrodeposition",

abstract = "In this paper, a novel approach is presented to obtain the cell sheets with mimicking the morphology of liver lobule tissue by electrodeposition method. We would take some steps to gain the sheets. It includes: 1) fabricate microelectrode which coated pattern onto fluorine-doped tin oxide (FTO) glass based on photolithography technique. 2) electrodeposition experiment which embedded with RLC-18 (rat liver) cells. 3) detach the sheet from the microelectrode by shaking it. 4) assemble 3D tissue structure. In the result, precise pattern in the sheet could be kept and the viability of the cells could be maintained. We also checked the height of the sheet. We believe the use of cell sheets by electrodeposition method is great potential in fabricating 3D cell structures.",

author = "Minmin Lu and Zeyang Liu and Masahiro Nakajima and Masaru Takeuchi and Yasuhisa Hasegawa and Toshio Fukuda and Qiang Huang",

note = "Publisher Copyright: {\textcopyright} 2016 IEEE.; 27th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016 ; Conference date: 28-11-2016 Through 30-11-2016",

year = "2017",

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day = "18",

doi = "10.1109/MHS.2016.7824181",

language = "English",

series = "2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016",

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Lu, M, Liu, Z, Nakajima, M, Takeuchi, M, Hasegawa, Y, Fukuda, T & Huang, Q 2017, Cell sheets fabrication with mimicking morphology of liver lobule tissue by electrodeposition. in 2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016., 7824181, 2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016, Institute of Electrical and Electronics Engineers Inc., 27th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016, Nagoya, Japan, 28/11/16. https://doi.org/10.1109/MHS.2016.7824181

Cell sheets fabrication with mimicking morphology of liver lobule tissue by electrodeposition. / Lu, Minmin; Liu, Zeyang; Nakajima, Masahiro et al.
2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016. Institute of Electrical and Electronics Engineers Inc., 2017. 7824181 (2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Cell sheets fabrication with mimicking morphology of liver lobule tissue by electrodeposition

AU - Lu, Minmin

AU - Liu, Zeyang

AU - Nakajima, Masahiro

AU - Takeuchi, Masaru

AU - Hasegawa, Yasuhisa

AU - Fukuda, Toshio

AU - Huang, Qiang

PY - 2017/1/18

Y1 - 2017/1/18

N2 - In this paper, a novel approach is presented to obtain the cell sheets with mimicking the morphology of liver lobule tissue by electrodeposition method. We would take some steps to gain the sheets. It includes: 1) fabricate microelectrode which coated pattern onto fluorine-doped tin oxide (FTO) glass based on photolithography technique. 2) electrodeposition experiment which embedded with RLC-18 (rat liver) cells. 3) detach the sheet from the microelectrode by shaking it. 4) assemble 3D tissue structure. In the result, precise pattern in the sheet could be kept and the viability of the cells could be maintained. We also checked the height of the sheet. We believe the use of cell sheets by electrodeposition method is great potential in fabricating 3D cell structures.

AB - In this paper, a novel approach is presented to obtain the cell sheets with mimicking the morphology of liver lobule tissue by electrodeposition method. We would take some steps to gain the sheets. It includes: 1) fabricate microelectrode which coated pattern onto fluorine-doped tin oxide (FTO) glass based on photolithography technique. 2) electrodeposition experiment which embedded with RLC-18 (rat liver) cells. 3) detach the sheet from the microelectrode by shaking it. 4) assemble 3D tissue structure. In the result, precise pattern in the sheet could be kept and the viability of the cells could be maintained. We also checked the height of the sheet. We believe the use of cell sheets by electrodeposition method is great potential in fabricating 3D cell structures.

UR - https://www.scopus.com/pages/publications/85013635340

U2 - 10.1109/MHS.2016.7824181

DO - 10.1109/MHS.2016.7824181

M3 - Conference contribution

AN - SCOPUS:85013635340

T3 - 2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016

BT - 2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 27th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016

Y2 - 28 November 2016 through 30 November 2016

ER -

Lu M, Liu Z, Nakajima M, Takeuchi M, Hasegawa Y, Fukuda T et al. Cell sheets fabrication with mimicking morphology of liver lobule tissue by electrodeposition. In 2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016. Institute of Electrical and Electronics Engineers Inc. 2017. 7824181. (2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016). doi: 10.1109/MHS.2016.7824181

Cell sheets fabrication with mimicking morphology of liver lobule tissue by electrodeposition

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