CeCl3·7H2O as an efficient catalyst for one-pot synthesis of β-amino ketones by three-component Mannich reaction

  • Yan Dai
  • , Bin Dong Li
  • , Heng Dao Quan
  • , Chun Xu Lü*
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)

Abstract

Cerium trichloride heptahydrate (CeCl3·7H2O) was found to be an efficient and recyclable catalyst for the three-component direct Mannich reaction of anilines and benzaldehydes with acetophenone. This protocol has advantages of high yield, no environmental pollution, mild condition, and simple work-up procedure.

Original languageEnglish
Pages (from-to)31-34
Number of pages4
JournalChinese Chemical Letters
Volume21
Issue number1
DOIs
Publication statusPublished - Jan 2010
Externally publishedYes

Keywords

  • Cerium trichloride heptahydrate
  • Lewis acid
  • Mannich reaction
  • β-Amino ketones

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