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Carboxymethyl chitin/organic rectorite composites based nanofibrous mats and their cell compatibility

  • Shangjing Xin
  • , Yuejun Li
  • , Wei Li
  • , Jing Du
  • , Rong Huang
  • , Yumin Du
  • , Hongbing Deng*
  • *Corresponding author for this work
  • Huazhong Agricultural University
  • Tangdu Hospital, Fourth Military Medical University
  • Wuhan University

Research output: Contribution to journal › Article › peer-review

Abstract

In this study, carboxymethyl chitin (CMC) - organic rectorite (OREC)/poly (vinyl alcohol) (PVA) composite nanofibrous mats were successfully prepared via electrospinning. SAXRD pattern showed that the interlayer distance of OREC was increased from 3.68 to 4.08 nm, which verified that polymer chains were intercalated into the interlayer of OREC. Field emission scanning electron microscopy, Fourier transform infrared spectra and energy-dispersive X-ray spectroscopy were used to characterize the morphology and microcosmic structure of nanofibrous mats. Thermal properties of mats were determined by differential scanning calorimetry. To evaluate the cell compatibility of mats, mouse lung fibroblast (L929) was chosen for cell attachment and spreading assay. The results shows that nanofibrous mats contained OREC have better thermal properties. Besides, the addition of OREC has little effect on the cell compatibility of nanofibrous mats.

Original languageEnglish
Pages (from-to)1069-1074
Number of pages6
JournalCarbohydrate Polymers
Volume90
Issue number2
DOIs
Publication statusPublished - 1 Oct 2012
Externally publishedYes

Keywords

  • Carboxymethyl chitin
  • Cell compatibility
  • Nanofibrous mats
  • Organic rectorite
  • Poly (vinyl alcohol)

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