Bio-Inspired Consecutive Photocatalyzed C-H Nitration of Arenes

Da Lie An, Chao Xu, Manman Wang*, Qinghai Shu, Xukai Zhou*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Concerned with traditional nitration methods requiring high temperatures, strong acids, or oxidizing agents, we developed an acid-free, selective photocatalytic nitration method using riboflavin tetraacetate and Fe(NO3)3·9H2O under visible light. This method efficiently nitrates various arenes and bioactive molecules with high selectivity and functional group tolerance, offering a sustainable alternative to traditional nitration techniques.

Original languageEnglish
Pages (from-to)4313-4324
Number of pages12
JournalJournal of Organic Chemistry
Volume90
Issue number12
DOIs
Publication statusPublished - 28 Mar 2025
Externally publishedYes

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