Automated construction system for 3D lattice structure based on alginate gel fiber containing living cells

Kenichi Ohara; Masaru Kojima; Akira Fukushima; Shun Onozaki; Mitsuhiro Horade; Masumi Yamada; Minoru Seki; Yasushi Mae; Tatsuo Arai

doi:10.20965/jrm.2013.p0665

Automated construction system for 3D lattice structure based on alginate gel fiber containing living cells

Kenichi Ohara
, Masaru Kojima
, Akira Fukushima
, Shun Onozaki
, Mitsuhiro Horade
, Masumi Yamada
, Minoru Seki
, Yasushi Mae
, Tatsuo Arai

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

The construction of 3D tissue is an important issue in regenerative medicine. While small 3D tissue has been realized in vitro, large functional 3D tissue has not been achieved due to difficulties in supplying oxygen and nutrients to the tissue. In this paper, we propose automated 3D construction based on hydrogel fiber to produce active 3D tissues. Results of several preliminary experiments in generating suitable hydrogel fibers have resulted in a lattice structure as an example of 3D tissue. In experiments in 3D structure construction, we observed cell growth in the constructed lattice confirming structure functionality.

Original language	English
Pages (from-to)	665-672
Number of pages	8
Journal	Journal of Robotics and Mechatronics
Volume	25
Issue number	4
DOIs	https://doi.org/10.20965/jrm.2013.p0665
Publication status	Published - Jun 2013
Externally published	Yes

Keywords

Alginate gel fiber
Lattice structure

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10.20965/jrm.2013.p0665

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title = "Automated construction system for 3D lattice structure based on alginate gel fiber containing living cells",

abstract = "The construction of 3D tissue is an important issue in regenerative medicine. While small 3D tissue has been realized in vitro, large functional 3D tissue has not been achieved due to difficulties in supplying oxygen and nutrients to the tissue. In this paper, we propose automated 3D construction based on hydrogel fiber to produce active 3D tissues. Results of several preliminary experiments in generating suitable hydrogel fibers have resulted in a lattice structure as an example of 3D tissue. In experiments in 3D structure construction, we observed cell growth in the constructed lattice confirming structure functionality.",

keywords = "Alginate gel fiber, Lattice structure",

author = "Kenichi Ohara and Masaru Kojima and Akira Fukushima and Shun Onozaki and Mitsuhiro Horade and Masumi Yamada and Minoru Seki and Yasushi Mae and Tatsuo Arai",

year = "2013",

month = jun,

doi = "10.20965/jrm.2013.p0665",

language = "English",

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T1 - Automated construction system for 3D lattice structure based on alginate gel fiber containing living cells

AU - Ohara, Kenichi

AU - Kojima, Masaru

AU - Fukushima, Akira

AU - Onozaki, Shun

AU - Horade, Mitsuhiro

AU - Yamada, Masumi

AU - Seki, Minoru

AU - Mae, Yasushi

AU - Arai, Tatsuo

PY - 2013/6

Y1 - 2013/6

N2 - The construction of 3D tissue is an important issue in regenerative medicine. While small 3D tissue has been realized in vitro, large functional 3D tissue has not been achieved due to difficulties in supplying oxygen and nutrients to the tissue. In this paper, we propose automated 3D construction based on hydrogel fiber to produce active 3D tissues. Results of several preliminary experiments in generating suitable hydrogel fibers have resulted in a lattice structure as an example of 3D tissue. In experiments in 3D structure construction, we observed cell growth in the constructed lattice confirming structure functionality.

AB - The construction of 3D tissue is an important issue in regenerative medicine. While small 3D tissue has been realized in vitro, large functional 3D tissue has not been achieved due to difficulties in supplying oxygen and nutrients to the tissue. In this paper, we propose automated 3D construction based on hydrogel fiber to produce active 3D tissues. Results of several preliminary experiments in generating suitable hydrogel fibers have resulted in a lattice structure as an example of 3D tissue. In experiments in 3D structure construction, we observed cell growth in the constructed lattice confirming structure functionality.

KW - Alginate gel fiber

KW - Lattice structure

UR - https://www.scopus.com/pages/publications/84881567925

U2 - 10.20965/jrm.2013.p0665

DO - 10.20965/jrm.2013.p0665

M3 - Article

AN - SCOPUS:84881567925

SN - 0915-3942

VL - 25

SP - 665

EP - 672

JO - Journal of Robotics and Mechatronics

JF - Journal of Robotics and Mechatronics

IS - 4

ER -

Automated construction system for 3D lattice structure based on alginate gel fiber containing living cells

Abstract

Keywords

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