Abstract
This paper studies the following system of differential equations modeling tumor angiogenesis in a bounded smooth domain Ω ⊂ ℝN (N = 1, 2): (Equation presented) where α, ρ, λ, μ and γ are positive parameters. For any reasonably regular initial data (p0, c0, w0), we prove the global boundedness (L∞-norm) of p via an iterative method. Furthermore, we investigate the long-time behavior of solutions to the above system under an additional mild condition, and improve previously known results. In particular, in the one-dimensional case, we show that the solution (p, c,w) converges to (1, 0, 1) with an explicit exponential rate as time tends to infinity.
| Original language | English |
|---|---|
| Pages (from-to) | 1387-1412 |
| Number of pages | 26 |
| Journal | Mathematical Models and Methods in Applied Sciences |
| Volume | 29 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 30 Jun 2019 |
Keywords
- Angiogenesis
- asymptotic behavior
- boundedness
- chemotaxis
- haptotaxis
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