Abstract
A series of novel chiral C2-symmetric bis (oxazoline) ligands have been synthesized. The copper and magnesium complexes, prepared in situ from copper (II)-triflate or magnesium triflate with the new enantiopure oxazoline ligands, were evaluated as chiral catalysts in the enantioselective Diels-Alder reaction of cyclopentadiene with N-crotenoyl-oxazolidin-2-one. Primary results showed that diastereoselectivity up to 94% and enantioselectivity up to 68% ee for endo products were observed respectively with these ligands.
Original language | English |
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Pages (from-to) | 597-599 |
Number of pages | 3 |
Journal | Chinese Journal of Chemistry |
Volume | 21 |
Issue number | 6 |
DOIs | |
Publication status | Published - Jun 2003 |
Externally published | Yes |
Keywords
- Asymmetic catalysis
- Bis(oxazoline)
- Dibenzo[a, c]cyclo-heptadiene
- Diels-Alder reaction