Application of Submicron Electrospray Emitter in Native Mass Spectrometry Analysis

Yu Zhang; Yang Tang; Wei Xu

doi:10.3969/j.issn.1004-4957.2021.02.009

Application of Submicron Electrospray Emitter in Native Mass Spectrometry Analysis

Yu Zhang
, Yang Tang
, Wei Xu^*

^*Corresponding author for this work

School of Medical Science and Engineering

Beijing Institute of Technology

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Native mass spectrometry has become one of the important tools for characterizing protein structures. Compared with traditional electrospray emitter (ESI emitter) , submicron electrospray emitters have various characteristics such as changing the charge-state distribution of ions and ion de- salting, which could be directly used to analyze the protein structures in the physiological environ- ment. In this review, the characteristics and applications of submicron electrospray emitters in native mass spectrometry analysis are discussed and summarized, and their future developments are also en- visioned.

Original language	English
Pages (from-to)	227-231
Number of pages	5
Journal	Journal of Instrumental Analysis
Volume	40
Issue number	2
DOIs	https://doi.org/10.3969/j.issn.1004-4957.2021.02.009
Publication status	Published - 2021

Keywords

charge-state distribution
ion desalting
native mass spectrometry
submicron electrospray emitters

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10.3969/j.issn.1004-4957.2021.02.009

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title = "Application of Submicron Electrospray Emitter in Native Mass Spectrometry Analysis",

abstract = "Native mass spectrometry has become one of the important tools for characterizing protein structures. Compared with traditional electrospray emitter (ESI emitter) , submicron electrospray emitters have various characteristics such as changing the charge-state distribution of ions and ion de- salting, which could be directly used to analyze the protein structures in the physiological environ- ment. In this review, the characteristics and applications of submicron electrospray emitters in native mass spectrometry analysis are discussed and summarized, and their future developments are also en- visioned.",

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AU - Zhang, Yu

AU - Tang, Yang

AU - Xu, Wei

PY - 2021

Y1 - 2021

N2 - Native mass spectrometry has become one of the important tools for characterizing protein structures. Compared with traditional electrospray emitter (ESI emitter) , submicron electrospray emitters have various characteristics such as changing the charge-state distribution of ions and ion de- salting, which could be directly used to analyze the protein structures in the physiological environ- ment. In this review, the characteristics and applications of submicron electrospray emitters in native mass spectrometry analysis are discussed and summarized, and their future developments are also en- visioned.

AB - Native mass spectrometry has become one of the important tools for characterizing protein structures. Compared with traditional electrospray emitter (ESI emitter) , submicron electrospray emitters have various characteristics such as changing the charge-state distribution of ions and ion de- salting, which could be directly used to analyze the protein structures in the physiological environ- ment. In this review, the characteristics and applications of submicron electrospray emitters in native mass spectrometry analysis are discussed and summarized, and their future developments are also en- visioned.

KW - charge-state distribution

KW - ion desalting

KW - native mass spectrometry

KW - submicron electrospray emitters

UR - https://www.scopus.com/pages/publications/85142174798

U2 - 10.3969/j.issn.1004-4957.2021.02.009

DO - 10.3969/j.issn.1004-4957.2021.02.009

M3 - Article

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SP - 227

EP - 231

JO - Journal of Instrumental Analysis

JF - Journal of Instrumental Analysis

IS - 2

ER -

Application of Submicron Electrospray Emitter in Native Mass Spectrometry Analysis

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Keywords

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