An expeditious synthesis of 1-substituted and cyclic taurines

Jiaxing Huang; Fei Wang; Da Ming Du; Jiaxi Xu

doi:10.1055/s-2005-869994

An expeditious synthesis of 1-substituted and cyclic taurines

Jiaxing Huang, Fei Wang, Da Ming Du, Jiaxi Xu^*

^*Corresponding author for this work

Peking University

Research output: Contribution to journal › Article › peer-review

52 Citations (Scopus)

Abstract

A series of 1-substituted taurines, including optically active taurines, were synthesized expeditiously from epoxides via episulfidation with potassium sulfocyanate, ring-opening with dibenzylamine, followed by oxidation with performic acid, and hydrogenolysis in the presence of palladium hydroxide on carbon powder. This method was also used for the synthesis of trans-cyclic taurines.

Original language	English
Pages (from-to)	2122-2128
Number of pages	7
Journal	Synthesis
Issue number	13
DOIs	https://doi.org/10.1055/s-2005-869994
Publication status	Published - 19 Aug 2005
Externally published	Yes

Keywords

Amino acid
Aminoalkanesulfonic acid
Episulfide
Epoxide
Synthesis
Taurine

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10.1055/s-2005-869994

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abstract = "A series of 1-substituted taurines, including optically active taurines, were synthesized expeditiously from epoxides via episulfidation with potassium sulfocyanate, ring-opening with dibenzylamine, followed by oxidation with performic acid, and hydrogenolysis in the presence of palladium hydroxide on carbon powder. This method was also used for the synthesis of trans-cyclic taurines.",

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author = "Jiaxing Huang and Fei Wang and Du, \{Da Ming\} and Jiaxi Xu",

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AU - Wang, Fei

AU - Du, Da Ming

AU - Xu, Jiaxi

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AB - A series of 1-substituted taurines, including optically active taurines, were synthesized expeditiously from epoxides via episulfidation with potassium sulfocyanate, ring-opening with dibenzylamine, followed by oxidation with performic acid, and hydrogenolysis in the presence of palladium hydroxide on carbon powder. This method was also used for the synthesis of trans-cyclic taurines.

KW - Amino acid

KW - Aminoalkanesulfonic acid

KW - Episulfide

KW - Epoxide

KW - Synthesis

KW - Taurine

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ER -

An expeditious synthesis of 1-substituted and cyclic taurines

Abstract

Keywords

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