An aptamer cross-linked hydrogel as a colorimetric platform for visual detection

Zhi Zhu; Cuichen Wu; Haipeng Liu; Yuan Zou; Xiaoling Zhang; Huaizhi Kang; Chaoyong James Yang; Weihong Tan

doi:10.1002/anie.200905570

An aptamer cross-linked hydrogel as a colorimetric platform for visual detection

Zhi Zhu^*, Cuichen Wu, Haipeng Liu, Yuan Zou, Xiaoling Zhang, Huaizhi Kang, Chaoyong James Yang, Weihong Tan

^*Corresponding author for this work

School of Chemistry and Chemical Engineering

Research output: Contribution to journal › Article › peer-review

343 Citations (Scopus)

Abstract

(Figure Presented) Cocaine cracked: The gel-sol transition of an enzyme-caged hydrogel has been efficiently controlled by target binding events, which trigger release of the enzyme to take part in its catalytic role for signal amplification (see picture). As low as 20 ng of cocaine can be visually detected within 10 min without any aid of sophisticated instrumentation.

Original language	English
Pages (from-to)	1052-1056
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	49
Issue number	6
DOIs	https://doi.org/10.1002/anie.200905570
Publication status	Published - 1 Feb 2010

Keywords

Aptamers
Cocaine
Colorimetric detection
Enzymes
Nanostructures

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10.1002/anie.200905570

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abstract = "(Figure Presented) Cocaine cracked: The gel-sol transition of an enzyme-caged hydrogel has been efficiently controlled by target binding events, which trigger release of the enzyme to take part in its catalytic role for signal amplification (see picture). As low as 20 ng of cocaine can be visually detected within 10 min without any aid of sophisticated instrumentation.",

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AU - Kang, Huaizhi

AU - Yang, Chaoyong James

AU - Tan, Weihong

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KW - Nanostructures

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An aptamer cross-linked hydrogel as a colorimetric platform for visual detection

Abstract

Keywords

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