Alkylaluminium-catalyzed regioselective hydrophosphinylation of α,β-unsaturated ketones into γ-ketophosphine oxides

Yiwen Chen; Ziyuan Pang; Gege Li; Xiaobo Yang; Wenliang Yan; Qifeng Li; Xuan Dong; Xiaoli Ma; Zhi Yang

doi:10.1039/d5cc01440a

Alkylaluminium-catalyzed regioselective hydrophosphinylation of α,β-unsaturated ketones into γ-ketophosphine oxides

Yiwen Chen, Ziyuan Pang, Gege Li, Xiaobo Yang, Wenliang Yan, Qifeng Li, Xuan Dong, Xiaoli Ma^*, Zhi Yang^*

^*Corresponding author for this work

School of Chemistry and Chemical Engineering, Beijing Institute of Technology

Research output: Contribution to journal › Article › peer-review

Abstract

A green method for regioselective hydrophosphinylation of α,β-unsaturated ketones using alkylaluminium compounds has been developed. It proceeds without acids, bases, or additives, yielding γ-ketophosphine oxides efficiently. This process offers excellent atom economy, functional group tolerance, and high yields in a short time.

Original language	English
Pages (from-to)	9666-9669
Number of pages	4
Journal	Chemical Communications
Volume	61
Issue number	53
DOIs	https://doi.org/10.1039/d5cc01440a
Publication status	Published - 30 May 2025
Externally published	Yes

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abstract = "A green method for regioselective hydrophosphinylation of α,β-unsaturated ketones using alkylaluminium compounds has been developed. It proceeds without acids, bases, or additives, yielding γ-ketophosphine oxides efficiently. This process offers excellent atom economy, functional group tolerance, and high yields in a short time.",

author = "Yiwen Chen and Ziyuan Pang and Gege Li and Xiaobo Yang and Wenliang Yan and Qifeng Li and Xuan Dong and Xiaoli Ma and Zhi Yang",

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AU - Chen, Yiwen

AU - Pang, Ziyuan

AU - Li, Gege

AU - Yang, Xiaobo

AU - Yan, Wenliang

AU - Li, Qifeng

AU - Dong, Xuan

AU - Ma, Xiaoli

AU - Yang, Zhi

PY - 2025/5/30

Y1 - 2025/5/30

N2 - A green method for regioselective hydrophosphinylation of α,β-unsaturated ketones using alkylaluminium compounds has been developed. It proceeds without acids, bases, or additives, yielding γ-ketophosphine oxides efficiently. This process offers excellent atom economy, functional group tolerance, and high yields in a short time.

AB - A green method for regioselective hydrophosphinylation of α,β-unsaturated ketones using alkylaluminium compounds has been developed. It proceeds without acids, bases, or additives, yielding γ-ketophosphine oxides efficiently. This process offers excellent atom economy, functional group tolerance, and high yields in a short time.

UR - http://www.scopus.com/inward/record.url?scp=105007907381&partnerID=8YFLogxK

U2 - 10.1039/d5cc01440a

DO - 10.1039/d5cc01440a

M3 - Article

AN - SCOPUS:105007907381

SN - 1359-7345

VL - 61

SP - 9666

EP - 9669

JO - Chemical Communications

JF - Chemical Communications

IS - 53

ER -

Alkylaluminium-catalyzed regioselective hydrophosphinylation of α,β-unsaturated ketones into γ-ketophosphine oxides

Abstract

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