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Advancements in Testing Strategies for COVID‐19

  • Rabia Asghar*
  • , Madiha Rasheed
  • , Jalees Ul Hassan
  • , Mohsin Rafique
  • , Mashooq Khan
  • , Yulin Deng*
  • *Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

The SARS‐CoV‐2 coronavirus, also known as the disease‐causing agent for COVID‐19, is a virulent pathogen that may infect people and certain animals. The global spread of COVID‐19 and its emerging variation necessitates the development of rapid, reliable, simple, and low‐cost diagnostic tools. Many methodologies and devices have been developed for the highly sensitive, selec-tive, cost‐effective, and rapid diagnosis of COVID‐19. This review organizes the diagnosis platforms into four groups: imaging, molecular‐based detection, serological testing, and biosensors. Each plat-form’s principle, advancement, utilization, and challenges for monitoring SARS‐CoV‐2 are dis-cussed in detail. In addition, an overview of the impact of variants on detection, commercially available kits, and readout signal analysis has been presented. This review will expand our understand-ing of developing advanced diagnostic approaches to evolve into susceptible, precise, and repro-ducible technologies to combat any future outbreak.

Original languageEnglish
Article number410
JournalBiosensors
Volume12
Issue number6
DOIs
Publication statusPublished - Jun 2022

Keywords

  • SARS‐CoV‐2
  • coronavirus
  • diagnosis
  • immunoassays
  • variants

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