Advance in aptamer research

Haiyan Xie; Xuechai Chen; Yulin Deng

Advance in aptamer research

Haiyan Xie^*
, Xuechai Chen
, Yulin Deng

^*Corresponding author for this work

School of Medical Science and Engineering

Beijing Institute of Technology

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Aptamer is a kind of synthetic oligonucleotides discriminated by in vitro screening, which is of high affinity and specificity with its ligands. Some new methods for efficient and fast detection for biochemical and biomedical purposes are being developed based on the molecular recognition of aptamers. In this paper, recent advance in the screening, chemical modification of aptamers and their applications in analytical chemistry and enzyme chemistry are reviewed.

Original language	English
Pages (from-to)	1026-1033
Number of pages	8
Journal	Progress in Chemistry
Volume	19
Issue number	6
Publication status	Published - Jun 2007

Keywords

Aptamers
Modification
SELEX

Cite this

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title = "Advance in aptamer research",

abstract = "Aptamer is a kind of synthetic oligonucleotides discriminated by in vitro screening, which is of high affinity and specificity with its ligands. Some new methods for efficient and fast detection for biochemical and biomedical purposes are being developed based on the molecular recognition of aptamers. In this paper, recent advance in the screening, chemical modification of aptamers and their applications in analytical chemistry and enzyme chemistry are reviewed.",

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T1 - Advance in aptamer research

AU - Xie, Haiyan

AU - Chen, Xuechai

AU - Deng, Yulin

PY - 2007/6

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AB - Aptamer is a kind of synthetic oligonucleotides discriminated by in vitro screening, which is of high affinity and specificity with its ligands. Some new methods for efficient and fast detection for biochemical and biomedical purposes are being developed based on the molecular recognition of aptamers. In this paper, recent advance in the screening, chemical modification of aptamers and their applications in analytical chemistry and enzyme chemistry are reviewed.

KW - Aptamers

KW - Modification

KW - SELEX

UR - https://www.scopus.com/pages/publications/34547294067

M3 - Article

AN - SCOPUS:34547294067

SN - 1005-281X

VL - 19

SP - 1026

EP - 1033

JO - Progress in Chemistry

JF - Progress in Chemistry

IS - 6

ER -

Advance in aptamer research

Abstract

Keywords

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