A theoretical investigation on two latest two-photon pH fluorescent probes

Zhong Xu, Ai Min Ren*, Dan Wang, Jing Fu Guo, Ji Kang Feng, Xiaoqiang Yu

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

Intracellular pH plays critical roles in cell, enzyme, and tissue activities, including proliferation and ion transport, and muscle contraction. Some pH fluorescent probes have been reported, but most of them are one-photon fluorescent probes, investigations on two-photon fluorescent probes are very rare. In this work, we thoroughly study two latest two-photon pH fluorescent probes and design two excellent two-photon pH fluorescent probes. One-photon properties of these pH fluorescent probes have been theoretically studied by using density functional theory (DFT) method. Their two-photon absorption (TPA) properties are calculated by using the DALTON program. The calculated results indicate that the designed CAE-CN can serve as a proper Photoinduced Charge Transfer two-photon pH fluorescent probe and the designed AP1 can serve as a proper Photoinduced Electron Transfer two-photon pH fluorescent probe.

Original languageEnglish
Pages (from-to)50-56
Number of pages7
JournalJournal of Photochemistry and Photobiology A: Chemistry
Volume293
DOIs
Publication statusPublished - 1 Nov 2014
Externally publishedYes

Keywords

  • CAE
  • pH fluorescent probes
  • Photoinduced Charge Transfer
  • Photoinduced Electron Transfer
  • PTCDI
  • Two-photon absorption

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