A SERS-active microfluidic device with tunable surface plasmon resonances

Bin Bin Xu; Zhuo Chen Ma; Huan Wang; Xue Qing Liu; Yong Lai Zhang; Xu Lin Zhang; Ran Zhang; Hao Bo Jiang; Hong Bo Sun

doi:10.1002/elps.201100309

A SERS-active microfluidic device with tunable surface plasmon resonances

Bin Bin Xu
, Zhuo Chen Ma
, Huan Wang
, Xue Qing Liu
, Yong Lai Zhang
, Xu Lin Zhang
, Ran Zhang
, Hao Bo Jiang
, Hong Bo Sun^*

^*Corresponding author for this work

Jilin University

Research output: Contribution to journal › Article › peer-review

59 Citations (Scopus)

Abstract

A surface-enhanced Raman scattering (SERS)-active microfluidic device with tunable surface plasmon resonances is presented here. It is constructed by silver grating substrates prepared by two-beam laser interference of photoresists and subsequent metal evaporation coating, as well as PDMS microchannel derived from soft lithography. By varying the period of gratings from 200 to 550nm, surface plasmon resonances (SPRs) from the metal gratings could be tuned in a certain range. When the SPRs match with the Raman excitation line, the highest enhancement factor of 2×10⁷ is achieved in the SERS detection. The SERS-active microchannel with tunable SPRs exhibits both high enhancement factor and reproducibility of SERS signals, and thus holds great promise for applications of on-chip SERS detection.

Original language	English
Pages (from-to)	3378-3384
Number of pages	7
Journal	Electrophoresis
Volume	32
Issue number	23
DOIs	https://doi.org/10.1002/elps.201100309
Publication status	Published - Nov 2011
Externally published	Yes

Keywords

Laser
Microfluidics
SERS
SPRs
Silver grating

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10.1002/elps.201100309

Cite this

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abstract = "A surface-enhanced Raman scattering (SERS)-active microfluidic device with tunable surface plasmon resonances is presented here. It is constructed by silver grating substrates prepared by two-beam laser interference of photoresists and subsequent metal evaporation coating, as well as PDMS microchannel derived from soft lithography. By varying the period of gratings from 200 to 550nm, surface plasmon resonances (SPRs) from the metal gratings could be tuned in a certain range. When the SPRs match with the Raman excitation line, the highest enhancement factor of 2×107 is achieved in the SERS detection. The SERS-active microchannel with tunable SPRs exhibits both high enhancement factor and reproducibility of SERS signals, and thus holds great promise for applications of on-chip SERS detection.",

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doi = "10.1002/elps.201100309",

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AU - Xu, Bin Bin

AU - Ma, Zhuo Chen

AU - Wang, Huan

AU - Liu, Xue Qing

AU - Zhang, Yong Lai

AU - Zhang, Xu Lin

AU - Zhang, Ran

AU - Jiang, Hao Bo

AU - Sun, Hong Bo

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N2 - A surface-enhanced Raman scattering (SERS)-active microfluidic device with tunable surface plasmon resonances is presented here. It is constructed by silver grating substrates prepared by two-beam laser interference of photoresists and subsequent metal evaporation coating, as well as PDMS microchannel derived from soft lithography. By varying the period of gratings from 200 to 550nm, surface plasmon resonances (SPRs) from the metal gratings could be tuned in a certain range. When the SPRs match with the Raman excitation line, the highest enhancement factor of 2×107 is achieved in the SERS detection. The SERS-active microchannel with tunable SPRs exhibits both high enhancement factor and reproducibility of SERS signals, and thus holds great promise for applications of on-chip SERS detection.

AB - A surface-enhanced Raman scattering (SERS)-active microfluidic device with tunable surface plasmon resonances is presented here. It is constructed by silver grating substrates prepared by two-beam laser interference of photoresists and subsequent metal evaporation coating, as well as PDMS microchannel derived from soft lithography. By varying the period of gratings from 200 to 550nm, surface plasmon resonances (SPRs) from the metal gratings could be tuned in a certain range. When the SPRs match with the Raman excitation line, the highest enhancement factor of 2×107 is achieved in the SERS detection. The SERS-active microchannel with tunable SPRs exhibits both high enhancement factor and reproducibility of SERS signals, and thus holds great promise for applications of on-chip SERS detection.

KW - Laser

KW - Microfluidics

KW - SERS

KW - SPRs

KW - Silver grating

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M3 - Article

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AN - SCOPUS:82755162011

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JO - Electrophoresis

JF - Electrophoresis

IS - 23

ER -

A SERS-active microfluidic device with tunable surface plasmon resonances

Abstract

Keywords

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