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A risk assessment model for type 2 diabetes in Chinese

  • Senlin Luo
  • , Longfei Han
  • , Ping Zeng
  • , Feng Chen
  • , Limin Pan
  • , Shu Wang
  • , Tiemei Zhang
  • Beijing Institute of Technology
  • Shanghai University
  • Nanjing Medical University

Research output: Contribution to journalArticlepeer-review

Abstract

Aims: To develop a risk assessment model for persons at risk from type 2 diabetes in Chinese. Materials and Methods: The model was generated from the cross-sectional data of 16246 persons aged from 20 years old and over. C4.5 algorithm and multivariate logistic regression were used for variable selection. Relative risk value combined with expert decision constructed a comprehensive risk assessment for evaluating the individual risk category. The validity of the model was tested by cross validation and a survey performed six years later with some participants. Results: Nine variables were selected as risk variables. A mathematical model was established to calculate the average probability of diabetes in each cluster's group divided by sex and age. A series of criteria combined with relative RR value (2.2) and level of risk variables stratified individuals into four risk groups (non, low, medium and high risk). The overall accuracy reached 90.99% evaluated by cross-validation inside the model population. The incidence of diabetes for each risk group increased from 1.5 (non-risk group) to 28.2(high-risk group) per one thousand persons per year with six years followup. Discussion: The model could determine the individual risk for type 2 diabetes by four risk degrees. This model could be used as a technique tool not only to support screening persons at different risk, but also to evaluate the result of the intervention.

Original languageEnglish
Article numbere104046
JournalPLoS ONE
Volume9
Issue number8
DOIs
Publication statusPublished - 7 Aug 2014

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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