A practical synthesis of sugar-derived cyclic nitrones: Powerful synthons for the synthesis of iminosugars

Wu Bao Wang; Mu Hua Huang; Yi Xian Li; Pei Xin Rui; Xiang Guo Hu; Wei Zhang; Jia Kun Su; Zhao Lan Zhang; Jian She Zhu; Wei Hua Xu; Xian Qing Xie; Yue Mei Jia; Chu Yi Yu

doi:10.1055/s-0029-1219189

A practical synthesis of sugar-derived cyclic nitrones: Powerful synthons for the synthesis of iminosugars

Wu Bao Wang
, Mu Hua Huang
, Yi Xian Li
, Pei Xin Rui
, Xiang Guo Hu
, Wei Zhang
, Jia Kun Su
, Zhao Lan Zhang
, Jian She Zhu
, Wei Hua Xu
, Xian Qing Xie
, Yue Mei Jia
, Chu Yi Yu^*

^*Corresponding author for this work

CAS - Institute of Chemistry
University of Chinese Academy of Sciences

Research output: Contribution to journal › Article › peer-review

53 Citations (Scopus)

Abstract

Sugar-derived cyclic nitrones were synthesized from the corresponding aldoses through an efficient and practical procedure involving a seven-step reaction sequence in good to excellent overall yield (10-42%). This synthetic strategy, requiring only inexpensive reagents, is easy to perform and hence suitable for large-scale preparations.

Original language	English
Pages (from-to)	488-492
Number of pages	5
Journal	Synlett
Issue number	3
DOIs	https://doi.org/10.1055/s-0029-1219189
Publication status	Published - 2010
Externally published	Yes

Keywords

Iminosugars
Nitrones
Sugar-derived cyclic nitrones
Synthesis

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10.1055/s-0029-1219189

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title = "A practical synthesis of sugar-derived cyclic nitrones: Powerful synthons for the synthesis of iminosugars",

abstract = "Sugar-derived cyclic nitrones were synthesized from the corresponding aldoses through an efficient and practical procedure involving a seven-step reaction sequence in good to excellent overall yield (10-42\%). This synthetic strategy, requiring only inexpensive reagents, is easy to perform and hence suitable for large-scale preparations.",

keywords = "Iminosugars, Nitrones, Sugar-derived cyclic nitrones, Synthesis",

author = "Wang, \{Wu Bao\} and Huang, \{Mu Hua\} and Li, \{Yi Xian\} and Rui, \{Pei Xin\} and Hu, \{Xiang Guo\} and Wei Zhang and Su, \{Jia Kun\} and Zhang, \{Zhao Lan\} and Zhu, \{Jian She\} and Xu, \{Wei Hua\} and Xie, \{Xian Qing\} and Jia, \{Yue Mei\} and Yu, \{Chu Yi\}",

year = "2010",

doi = "10.1055/s-0029-1219189",

language = "English",

pages = "488--492",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

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TY - JOUR

T1 - A practical synthesis of sugar-derived cyclic nitrones

T2 - Powerful synthons for the synthesis of iminosugars

AU - Wang, Wu Bao

AU - Huang, Mu Hua

AU - Li, Yi Xian

AU - Rui, Pei Xin

AU - Hu, Xiang Guo

AU - Zhang, Wei

AU - Su, Jia Kun

AU - Zhang, Zhao Lan

AU - Zhu, Jian She

AU - Xu, Wei Hua

AU - Xie, Xian Qing

AU - Jia, Yue Mei

AU - Yu, Chu Yi

PY - 2010

Y1 - 2010

N2 - Sugar-derived cyclic nitrones were synthesized from the corresponding aldoses through an efficient and practical procedure involving a seven-step reaction sequence in good to excellent overall yield (10-42%). This synthetic strategy, requiring only inexpensive reagents, is easy to perform and hence suitable for large-scale preparations.

AB - Sugar-derived cyclic nitrones were synthesized from the corresponding aldoses through an efficient and practical procedure involving a seven-step reaction sequence in good to excellent overall yield (10-42%). This synthetic strategy, requiring only inexpensive reagents, is easy to perform and hence suitable for large-scale preparations.

KW - Iminosugars

KW - Nitrones

KW - Sugar-derived cyclic nitrones

KW - Synthesis

UR - https://www.scopus.com/pages/publications/76249094140

U2 - 10.1055/s-0029-1219189

DO - 10.1055/s-0029-1219189

M3 - Article

AN - SCOPUS:76249094140

SN - 0936-5214

SP - 488

EP - 492

JO - Synlett

JF - Synlett

IS - 3

ER -

A practical synthesis of sugar-derived cyclic nitrones: Powerful synthons for the synthesis of iminosugars

Abstract

Keywords

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