A practical synthesis of sugar-derived cyclic nitrones: Powerful synthons for the synthesis of iminosugars

Wu Bao Wang; Mu Hua Huang; Yi Xian Li; Pei Xin Rui; Xiang Guo Hu; Wei Zhang; Jia Kun Su; Zhao Lan Zhang; Jian She Zhu; Wei Hua Xu; Xian Qing Xie; Yue Mei Jia; Chu Yi Yu

doi:10.1055/s-0029-1219189

A practical synthesis of sugar-derived cyclic nitrones: Powerful synthons for the synthesis of iminosugars

Wu Bao Wang, Mu Hua Huang, Yi Xian Li, Pei Xin Rui, Xiang Guo Hu, Wei Zhang, Jia Kun Su, Zhao Lan Zhang, Jian She Zhu, Wei Hua Xu, Xian Qing Xie, Yue Mei Jia, Chu Yi Yu^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

50 Citations (Scopus)

Abstract

Sugar-derived cyclic nitrones were synthesized from the corresponding aldoses through an efficient and practical procedure involving a seven-step reaction sequence in good to excellent overall yield (10-42%). This synthetic strategy, requiring only inexpensive reagents, is easy to perform and hence suitable for large-scale preparations.

Original language	English
Pages (from-to)	488-492
Number of pages	5
Journal	Synlett
Issue number	3
DOIs	https://doi.org/10.1055/s-0029-1219189
Publication status	Published - 2010
Externally published	Yes

Keywords

Iminosugars
Nitrones
Sugar-derived cyclic nitrones
Synthesis

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10.1055/s-0029-1219189

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title = "A practical synthesis of sugar-derived cyclic nitrones: Powerful synthons for the synthesis of iminosugars",

abstract = "Sugar-derived cyclic nitrones were synthesized from the corresponding aldoses through an efficient and practical procedure involving a seven-step reaction sequence in good to excellent overall yield (10-42\%). This synthetic strategy, requiring only inexpensive reagents, is easy to perform and hence suitable for large-scale preparations.",

keywords = "Iminosugars, Nitrones, Sugar-derived cyclic nitrones, Synthesis",

author = "Wang, \{Wu Bao\} and Huang, \{Mu Hua\} and Li, \{Yi Xian\} and Rui, \{Pei Xin\} and Hu, \{Xiang Guo\} and Wei Zhang and Su, \{Jia Kun\} and Zhang, \{Zhao Lan\} and Zhu, \{Jian She\} and Xu, \{Wei Hua\} and Xie, \{Xian Qing\} and Jia, \{Yue Mei\} and Yu, \{Chu Yi\}",

year = "2010",

doi = "10.1055/s-0029-1219189",

language = "English",

pages = "488--492",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

number = "3",

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TY - JOUR

T1 - A practical synthesis of sugar-derived cyclic nitrones

T2 - Powerful synthons for the synthesis of iminosugars

AU - Wang, Wu Bao

AU - Huang, Mu Hua

AU - Li, Yi Xian

AU - Rui, Pei Xin

AU - Hu, Xiang Guo

AU - Zhang, Wei

AU - Su, Jia Kun

AU - Zhang, Zhao Lan

AU - Zhu, Jian She

AU - Xu, Wei Hua

AU - Xie, Xian Qing

AU - Jia, Yue Mei

AU - Yu, Chu Yi

PY - 2010

Y1 - 2010

N2 - Sugar-derived cyclic nitrones were synthesized from the corresponding aldoses through an efficient and practical procedure involving a seven-step reaction sequence in good to excellent overall yield (10-42%). This synthetic strategy, requiring only inexpensive reagents, is easy to perform and hence suitable for large-scale preparations.

AB - Sugar-derived cyclic nitrones were synthesized from the corresponding aldoses through an efficient and practical procedure involving a seven-step reaction sequence in good to excellent overall yield (10-42%). This synthetic strategy, requiring only inexpensive reagents, is easy to perform and hence suitable for large-scale preparations.

KW - Iminosugars

KW - Nitrones

KW - Sugar-derived cyclic nitrones

KW - Synthesis

UR - https://www.scopus.com/pages/publications/76249094140

U2 - 10.1055/s-0029-1219189

DO - 10.1055/s-0029-1219189

M3 - Article

AN - SCOPUS:76249094140

SN - 0936-5214

SP - 488

EP - 492

JO - Synlett

JF - Synlett

IS - 3

ER -

A practical synthesis of sugar-derived cyclic nitrones: Powerful synthons for the synthesis of iminosugars

Abstract

Keywords

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