A Portable Illumination Device for Photodynamic Therapy of the Oral Cavity*

Jiyuan Xiong; Xu Wang; Xiaoming Hu; Ying Han; Qin Li

doi:10.1142/9789811293696_0002

A Portable Illumination Device for Photodynamic Therapy of the Oral Cavity*

Jiyuan Xiong
, Xu Wang
, Xiaoming Hu
, Ying Han^*
, Qin Li

^*Corresponding author for this work

School of Medical Science and Engineering

Beijing Institute of Technology
Peking University

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Photodynamic therapy (PDT) is a minimally invasive method for treating oral leukoplakia. In this paper, we propose a portable PDT device consisting of a flexible circuit board with a liquid flow cooling module on the back. The light source sizewas 17mm × 11mm × 4 mm, and the irradiation area of the light source was up to 100mm². The irradiance range of this device was from 10mW/cm² to 100mW/cm². Simulation and experimental results showed that the irradiance coefficient variation for a treatment area of 81mm² was less than 7%. At an irradiance of 100mW/cm², a device surface temperature of lower than 42°C can be achieved to satisfy the safety requirements under the conditions that the temperature of cooling liquid is 10°C and the liquid flow speed is above 12mL/min.

Original language	English
Title of host publication	Enhanced Photodynamic Therapy Volume 1
Subtitle of host publication	Basics and Technical Developments: Volume 2: Biology and Advancements to Clinical Translation
Publisher	World Scientific Publishing Co.
Pages	18-34
Number of pages	17
Volume	1-2
ISBN (Electronic)	9789811293702
ISBN (Print)	9789811299636
DOIs	https://doi.org/10.1142/9789811293696_0002
Publication status	Published - 1 Jan 2024

Keywords

illumination device
irradiance uniformity
oral leukoplakia
Photodynamic therapy

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10.1142/9789811293696_0002

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title = "A Portable Illumination Device for Photodynamic Therapy of the Oral Cavity*",

abstract = "Photodynamic therapy (PDT) is a minimally invasive method for treating oral leukoplakia. In this paper, we propose a portable PDT device consisting of a flexible circuit board with a liquid flow cooling module on the back. The light source sizewas 17mm × 11mm × 4 mm, and the irradiation area of the light source was up to 100mm2. The irradiance range of this device was from 10mW/cm2 to 100mW/cm2. Simulation and experimental results showed that the irradiance coefficient variation for a treatment area of 81mm2 was less than 7\%. At an irradiance of 100mW/cm2, a device surface temperature of lower than 42°C can be achieved to satisfy the safety requirements under the conditions that the temperature of cooling liquid is 10°C and the liquid flow speed is above 12mL/min.",

keywords = "illumination device, irradiance uniformity, oral leukoplakia, Photodynamic therapy",

author = "Jiyuan Xiong and Xu Wang and Xiaoming Hu and Ying Han and Qin Li",

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doi = "10.1142/9789811293696\_0002",

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A Portable Illumination Device for Photodynamic Therapy of the Oral Cavity*. / Xiong, Jiyuan; Wang, Xu; Hu, Xiaoming et al.
Enhanced Photodynamic Therapy Volume 1: Basics and Technical Developments: Volume 2: Biology and Advancements to Clinical Translation. Vol. 1-2 World Scientific Publishing Co., 2024. p. 18-34.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

TY - CHAP

T1 - A Portable Illumination Device for Photodynamic Therapy of the Oral Cavity*

AU - Xiong, Jiyuan

AU - Wang, Xu

AU - Hu, Xiaoming

AU - Han, Ying

AU - Li, Qin

PY - 2024/1/1

Y1 - 2024/1/1

N2 - Photodynamic therapy (PDT) is a minimally invasive method for treating oral leukoplakia. In this paper, we propose a portable PDT device consisting of a flexible circuit board with a liquid flow cooling module on the back. The light source sizewas 17mm × 11mm × 4 mm, and the irradiation area of the light source was up to 100mm2. The irradiance range of this device was from 10mW/cm2 to 100mW/cm2. Simulation and experimental results showed that the irradiance coefficient variation for a treatment area of 81mm2 was less than 7%. At an irradiance of 100mW/cm2, a device surface temperature of lower than 42°C can be achieved to satisfy the safety requirements under the conditions that the temperature of cooling liquid is 10°C and the liquid flow speed is above 12mL/min.

AB - Photodynamic therapy (PDT) is a minimally invasive method for treating oral leukoplakia. In this paper, we propose a portable PDT device consisting of a flexible circuit board with a liquid flow cooling module on the back. The light source sizewas 17mm × 11mm × 4 mm, and the irradiation area of the light source was up to 100mm2. The irradiance range of this device was from 10mW/cm2 to 100mW/cm2. Simulation and experimental results showed that the irradiance coefficient variation for a treatment area of 81mm2 was less than 7%. At an irradiance of 100mW/cm2, a device surface temperature of lower than 42°C can be achieved to satisfy the safety requirements under the conditions that the temperature of cooling liquid is 10°C and the liquid flow speed is above 12mL/min.

KW - illumination device

KW - irradiance uniformity

KW - oral leukoplakia

KW - Photodynamic therapy

UR - https://www.scopus.com/pages/publications/85211274688

U2 - 10.1142/9789811293696_0002

DO - 10.1142/9789811293696_0002

M3 - Chapter

AN - SCOPUS:85211274688

SN - 9789811299636

VL - 1-2

SP - 18

EP - 34

BT - Enhanced Photodynamic Therapy Volume 1

PB - World Scientific Publishing Co.

ER -

A Portable Illumination Device for Photodynamic Therapy of the Oral Cavity*

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Keywords

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