TY - JOUR
T1 - A hydra tentacle-inspired hydrogel with underwater ultra-stretchability for adhering adipose surfaces
AU - Wang, Hao
AU - Su, Xing
AU - Chai, Zhihua
AU - Tian, Zhuoling
AU - Xie, Wenyue
AU - Wang, Yanxia
AU - Wan, Zhuo
AU - Deng, Meigui
AU - Yuan, Zuoying
AU - Huang, Jianyong
N1 - Publisher Copyright:
© 2021 Elsevier B.V.
PY - 2022/1/15
Y1 - 2022/1/15
N2 - Adhesive hydrogels hold great significance in various biomedical applications. However, the maintenance of high extensibility and adhesion to adipose matters still remain challenging. Inspired by hydra tentacles, we utilise flexible polymeric ionic crosslinkers for constructing densely crosslinked networks. The derived hydrogel was ultra-stretchable (over 54 times) even in the fully swollen state in water. Due to dense electrostatic bonding sites and hydrophobic phases, it displayed fast (~30 sec), repeatable and long-lasting (over 14 days) underwater adhesion to adipose surfaces such as fat, octopus and fish epidermis in aqueous environments. Moreover, the excellent cytocompatibility and antibacterial ability made it suitable for a variety of applications related to biomedicine and flexible electronics. This biomimetic work addresses new possibility for the design rationale for highly stretchable and lipophilic underwater adhesives.
AB - Adhesive hydrogels hold great significance in various biomedical applications. However, the maintenance of high extensibility and adhesion to adipose matters still remain challenging. Inspired by hydra tentacles, we utilise flexible polymeric ionic crosslinkers for constructing densely crosslinked networks. The derived hydrogel was ultra-stretchable (over 54 times) even in the fully swollen state in water. Due to dense electrostatic bonding sites and hydrophobic phases, it displayed fast (~30 sec), repeatable and long-lasting (over 14 days) underwater adhesion to adipose surfaces such as fat, octopus and fish epidermis in aqueous environments. Moreover, the excellent cytocompatibility and antibacterial ability made it suitable for a variety of applications related to biomedicine and flexible electronics. This biomimetic work addresses new possibility for the design rationale for highly stretchable and lipophilic underwater adhesives.
KW - Biomimetic hydrogel
KW - Cytocompatibility
KW - Long-ranged attractive forces
KW - Ultra-stretchability
KW - Underwater adhesion to adipose surfaces
UR - http://www.scopus.com/inward/record.url?scp=85111346743&partnerID=8YFLogxK
U2 - 10.1016/j.cej.2021.131049
DO - 10.1016/j.cej.2021.131049
M3 - Article
AN - SCOPUS:85111346743
SN - 1385-8947
VL - 428
JO - Chemical Engineering Journal
JF - Chemical Engineering Journal
M1 - 131049
ER -