Abstract
A new method for the cleavage of amide C-N bond was studied in this paper. Some factors such as reaction temperature, quantity Of CuCl 2and kind of Lewis acid affected the cleavage of amide C-N bond are discussed. And the possible mechanism of C-N bond broken is proposed. This new method possesses lower temperature, less acid and milder conditions.
Original language | English |
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Pages (from-to) | 1126-1130 |
Number of pages | 5 |
Journal | Chinese Journal of Organic Chemistry |
Volume | 32 |
Issue number | 6 |
DOIs | |
Publication status | Published - Jun 2012 |
Keywords
- Amide
- Catalysis
- Cleavage of c-n bond
- Lewis acid