A convenient method for cleavage of amide c-n bond

Yingfei Wei*, Daxing Shi, Zhen Wei, Juan Xu, Jiarong Li

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

A new method for the cleavage of amide C-N bond was studied in this paper. Some factors such as reaction temperature, quantity Of CuCl 2and kind of Lewis acid affected the cleavage of amide C-N bond are discussed. And the possible mechanism of C-N bond broken is proposed. This new method possesses lower temperature, less acid and milder conditions.

Original languageEnglish
Pages (from-to)1126-1130
Number of pages5
JournalChinese Journal of Organic Chemistry
Volume32
Issue number6
DOIs
Publication statusPublished - Jun 2012

Keywords

  • Amide
  • Catalysis
  • Cleavage of c-n bond
  • Lewis acid

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