新型分子印迹生物传感器在癌症生物标志物中的应用

Cancer biomarkers, as specific measurable indicators in the body, can monitor cancer health through their own changes, and are of great significance for cancer prevention, early diagnosis and precise treatment. Therefore, rapid detection and precise analysis of typical disease markers have become a hot field of scientific research and clinical diagnosis. Molecular imprinting-based bio-sensing technology is expected to become a new method for rapid detection of disease markers due to its high sensitivity, fast response, strong specificity and low cost, and has been widely studied in the field of cancer clinical analysis. This review introduces the molecularly imprinted polymer synthetic methods and strategies, the sensor technology and means through the combination of molecular imprinting with electrochemical, surface plasma resonance and optical analysis, and the application of molecularly imprinted sensor in prostate cancer, breast cancer, liver cancer and other cancers biomarkers. Finally, this review summarizes the application status of molecularly imprinted sensors in the analysis and detection of cancer biomarkers at home and abroad, and puts forward the prospect of its development in the future.