Weng Yu-hwa, Special Associate Research Fellow, Assistant Professor (Supervisor of Postgraduate Students)
Subject: Biomedical Engineering
Direction: Nucleic acid Drug Design and Delivery
E-mail :wengyh@bit.edu.cn
Office Address: 402, Building 7, Beijing Institute of Technology, No.5 Zhongguancun South Street, Haidian District, Beijing
Weng Yuhua, a member of the China Democratic League, is a special associate researcher and master tutor at the School of Medical Technology, Beijing Institute of Technology. Research directions: (1) Development of nucleic acid molecule-based drugs and imaging probes, including application research of nucleic acid drugs based on small interfering RNA, mRNA, ASO, CRISPR/Cas gene editing system, aptamer, etc.; (2) Nucleic acid delivery technology, including molecular conjugation technology, exosomes, degradable polymers, lipid nanoparticle delivery technology, etc.; (3) AI-assisted nucleic acid drug design and optimization, and developed artificial intelligence algorithms for sequence optimization and delivery formulation optimization of mRNA and other nucleic acid drugs. In the past five years, he has published more than 10 SCI papers as the first/corresponding author, including 3 papers with high ESI citation and 8 papers with impact factor >10; Has undertaken the National Natural Science Foundation, Beijing Natural Science Foundation, key research and development plan sub-projects, horizontal projects of pharmaceutical enterprises, etc. Obtained 3 authorized patents; He is a young editorial board member of Wiley Publishing's journal Exploration and a member of several academic societies. The team website: https://www.x-mol.com/groups/Yuanyu_Huang-BIT Welcome excellent students from biology, materials, chemistry, medicine, computer and other majors to join the nucleic acid biological diagnosis and treatment team!

(1) Development of drugs and imaging probes based on nucleic acid molecules, including small interfering RNA, mRNA, ASO, CRISPR/Cas gene editing system, aptamer, etc.;
(2) Nucleic acid delivery technology, including molecular conjugation technology, exosomes, degradable polymers, lipid nanoparticle delivery technology, etc.
(3) AI-assisted nucleic acid drug design and optimization, and developed artificial intelligence algorithms for sequence optimization and delivery formulation optimization of mRNA and other nucleic acid drugs.

2022.2-2023.2 Visiting Scholar, SPMS School, Nanyang Technological University, Singapore
2014.9-2017.6 University of Chinese Academy of Sciences & National NanoScience Center Ph. D. Major: Materials Science
2007.9-2010.6 Shanghai Normal University Master Major: Microbiology

2022.2-2023.2 Visiting Scholar, SPMS School, Nanyang Technological University, Singapore
2014.9-2017.6 University of Chinese Academy of Sciences & National NanoScience Center Ph. D. Major: Materials Science
2007.9-2010.6 Shanghai Normal University Master Major: Microbiology
2019.10-present Special Associate Researcher and Assistant Professor, School of Medical Technology, Beijing Institute of Technology
2017.9-2019.9 Postdoctoral Fellow, Institute of Frontier and Interdisciplinary Science, Beijing Institute of Technology
2011.8-2014.8 Researcher of School of Optometry and Hospital of Wenzhou Medical University