Calculated based on number of publications stored in Pure and citations from Scopus
20092025

Research activity per year

Personal profile

Personal profile

He has presided over a number of projects such as the National Natural Science Foundation, the National Key Research and Development Program, the key research projects of Frontier Sciences of the Chinese Academy of Sciences, and the National Defense Science and Technology Innovation projects of the Chinese Academy of Sciences. In 2014, he was elected to the "Youth Innovation Promotion Association of Chinese Academy of Sciences", and in 2018, he was named an excellent member of the Youth Innovation Promotion Association of Chinese Academy of Sciences, and he was invited to give more than 10 conferences/invited reports at international and domestic academic conferences. Obtained three medical device registration certificates. He has published more than 50 research papers in important international academic journals such as Nature Nanotechnology, Nature protocols, ACS Nano, and PNAS, and his research results have been selected as "Top Ten Scientific Advances in China". In 2017, he won the National Science Fund for Outstanding Young People, and in 2018, he won the third Zhongyuan Union Life Medicine Award. Currently, he is a member of four academic organizations, namely, Chinese Medical Device Industry Union - On-site Rapid Detection (POCT) Branch, Chinese Biophysical Society - Nano-enzyme Branch, Chinese Medical and Health Culture Association - Medical and Industrial Integration Branch and Chinese Biomedical Engineering Society Committee.

Research Interests

Through the intersection of tumor biology and biomimetic nanotechnology, the research and development of highly sensitive and highly specific molecular targeting probes have been carried out.

Education

2005-03 to 2008-03, Center for Ecological Research, Chinese Academy of Sciences, PhD, Molecular Biology, Supervisor: Professor Lianghong Guo
2002-09 to 2005-03, Beijing Institute of Technology, Analytical Chemistry, Master, Supervisor: Professor Qi Meiling
1997-09 to 2001-07, Chemical Engineering and Technology, Shandong Institute of Light Industry, B.S.

Professional Experience

2019-06-present, School of Materials, Beijing Institute of Technology, Professor
2015-01 to 2019-06, Key Laboratory of Protein and Peptide Drugs, Institute of Biophysics, Chinese Academy of Sciences, Researcher
2010-06-2014-12, Key Laboratory of Protein and Peptide Drugs, Institute of Biophysics, Chinese Academy of Sciences, Associate Researcher
Dr. Donald J. Hnatowich, Postdoctoral Fellow, School of Medicine, University of Massachusetts, USA (2008-03-2010-06)

Research Achievement

1. Ji, S.; Jiang, B.; Hao, H.; Chen, Y.; Dong, J.; Mao, Y.; Zhang, Z.; Gao, R.; Chen, W.; Zhang, R.; Liang, Q.; Li, H.; Liu, S.; Wang, Y.; Zhang, Q.; Gu, L.; Duan, D.; Liang, M.*; Wang, D.*; Yan, X.*; Li, Y*. Matching the kinetics of natural enzymes with a single-atom iron nanozyme. Nat. Catal. , 2021, 4 (5), 407-417.
2. Zhang, J., Cheng, D., He, J. Hong, J.; Yuan, C.; Liang, M.*; Cargo loading within ferritin nanocages in preparation for tumor-targeted delivery. Nat. Protoc. , 2021, 16, 4878-4896.
3. Chen,Y.; Wang,P.; Hao, H.; Hong, J.; Li, H.; Ji, S.; Liang, M.*; Wang, D.*;, Yadong Li. Thermal Atomization of Platinum Nanoparticles into Single Atoms: An effective strategy for engineering high-performance nanozymes. J. Am. Chem. Soc. 2021, https://doi.org/10.1021/jacs.1c08581.
4. Wang, P. X.; Liu, S. L.; Hu, M. X.; Duan, D. M.; He, J. Y.; Hong, J. J.; Lv, R. Choi, H. S.*; Yan, X. Y.*; Liang, M*. Peroxidase‐like nanozymes induce a novel form of cell death and inhibit tumor growth in vivo. Adv. Funct. Mater. , 2020, 30, 2000647-2000656.
5. Jiang B, Duan D, Liang M*, Yan X*, Standardized assays for determining the catalytic activity and kinetics of peroxidase-like nanozymes, Nat. Protoc. , 2018, 13: 1506-1520.
6. Song, N.; Zhang, J.; Zhai, J.; Hong, J.; Yuan, C.; Liang, M.*; Ferritin: A multifunctional nanoplatform for biological detection, imaging diagnosis, and drug delivery, Acc. Chem. Res. 2021, 54, 17, 3313-3325.
7. Fan K, Cao C, Pan Y, Lu D, Yang D, Feng J, Song L, Liang M*, Yan X*. Magnetoferritin nanoparticles for targeting and visualizing tumour tissues. Nat. Nanotech. 2012, 7:459-64.
8. Liang M, H Tan, J Zhou, T Wang, D Duan,Cheng D*, Choi HS*, Yan X*. , et al. Bioengineered H-Ferritin nanocages for quantitative imaging of vulnerable plaques in atherosclerosis, ACS nano, 2018, 12 (9), 9300-9308
9. Liang M, Fan K, Zhou M, Duan D, Zheng J, Yang D, Feng J, Yan X, H-ferritin-nanocaged doxorubicin nanoparticles specifically target and kill tumors with a single-dose injection. PNAS. 2014,111(41):14900-5.
10. Liang, M.*; Yan X*; Nanozymes: from new concepts, mechanisms, and standards to applications. Acc. Chem. Res. 2019, 52, 8, 2190-2200.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 7 - Affordable and Clean Energy
  • SDG 16 - Peace, Justice and Strong Institutions

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