Mainly engaged in biocatalysis and synthetic biology, industry-university-research related work. In view of the shortage of resources, dependence on cultivated land and long cycle of traditional plant extraction methods, the research work focuses on the biosynthesis, biomodification and industrial application of plant natural products and their derivatives, the establishment of microbial cell factories for the synthesis of plant natural products, the development of efficient tools for metabolic pathway assembly, and the creation of efficient platforms for microbial synthesis of plant natural products. At present, he has presided over and participated in the National Natural Science Foundation, the National 863 project, the enterprise horizontal project and the key research and development plan of the Ministry of Science and Technology, published 28 SCI papers and authorized 6 patents.

(1) Enzyme molecular rational design, molecular evolution, structural analysis and catalytic mechanism research.
(2) Biosynthesis of high value-added plant-derived natural products such as glycyrrhizic acid, diosgenin, echinacea, and cell factory construction of plant natural products.
(3) Functional microbial genomics, transcriptomics and other bioinformatics analysis

2009.09-2015.07 Beijing Institute of Technology, Major in Biochemistry, Doctor of Engineering
2006.09-2009.07 Shihezi University, Major in Processing and Storage of Agricultural products, Master of Engineering
2002.09-2006.07 Beijing Institute of Technology, Bioengineering, Bachelor of Engineering

2018.09-present Beijing Institute of Technology School of Chemistry and Chemical Engineering, Pre-appointed Associate Professor
2015.10-2018.09 Beijing Institute of Technology, Chemistry, Postdoc

Undertaking project
1. National Key Research and Development Plan "Green biological manufacturing" key project, 2021YFC2102800, large-scale application of new industrial enzyme immobilization technology, 1 million, 2022/01-2024/12, sub-project leader.
2. National Key Research and Development Plan "Synthetic Biology" key project, 2018YFA0901800, Construction and Application Demonstration of microbial cell Factory for Synthetic Plant Natural Products, 1.31 million, 2019/07-2024/06, sub-project leader.
3. Youth Science Foundation of National Natural Science Foundation of China, 21606019, Transformation Mechanism of β-glucuronidase hydrolysis and Synthesis properties, 2017/01-2019/12,200,000 Yuan, Host.
4. Horizontal project of enterprises and public institutions, pilot research and development of Biopreparation of glycyrrhetinic acid and GAMG, 2016/10-2021/10, 5 million yuan, host.
5. Key Project of National Natural Science Foundation of China, 21736002, Transmembrane transport and metabolic mass transfer Enhancement during Microbial synthesis of terpene Compounds, 2019/01-2022/12, 3.2 million yuan, participated.
6. Project of the Department of Science and Technology of Xinjiang Autonomous Region, Bioenzyme Preparation of glycyrrhetinic acid and its Derivatives and Industrialization, 2017/1-2019/12, 100,000 yuan, presided over.
7 Beijing Institute of Technology Young Teachers Academic Start-up Project, Molecular Mechanism of the Synthesis of triterpene skeleton Diversity catalyzed by squalene oxide cyclase, 2019/1-2021/12,600 yuan, hosted.
Research Results
Presided over 1 project of National Natural Science Foundation and undertook 2 horizontal cooperation projects of enterprises; Participated in 3 National Natural Science Foundation projects, undertook the national key research and development program "green biological manufacturing" key projects, the national key research and development program "synthetic biology" key projects 2. So far, he has published 40 academic papers in academic journals and conferences at home and abroad, and granted 5 patents.
Representative Papers
1. Sun Jiachen, Sun Wentao, Zhang Genlin*, Lv Bo*, Li Chun*. High efficient production of plant flavonoids by microbial cell factories: Challenges and opportunities. Metabolic Engineering. 2022, 70, 143-154.
2. Zhang Teng, Sun Yi, Ma, Zhidong, Zhang Jinwen, Lv Bo*, Li Chun*. Developing iterative and quantified transgenic manipulations of non-conventional filamentous fungus Talaromyces pinophilus Li-93. Biochemical Engineering Journal. 2022, 179, 108317.
3. Xu Ke, Zhao Yujia, Ahmad, Nadeem, Wang, Jinnan, Lv Bo*, Li Chun*. O-glycosyltransferases from homo sapiens contributes to the biosynthesis of glycyrrhetic acid 3-o-mono-β-d-Glucuronide and glycyrrhizin in saccharomyces cerevisiae. Synthetic and Systems Biotechnology, 2021, 6(3), 173-179.
4. Chen L, Pang Y, Luo Y,Cheng X, Lv B*, Li C*, Separation and purification of plant terpenoids from biotransformation. Eng Life Sci. 2021; 1-15.
5. Haoran Liu, Nadeem Ahmad, Bo Lv*, Chun Li*. Advances in production and structural derivatization of the promising molecule ursolic acid [J]. Biotechnology Journal. 2021,16(11).
6. Liu Mingzhu, Yu Jing, Lv Bo*, Hou Yuhui, Liu Xinhe, Feng Xudong*, & Li Chun. Improving the activity and thermostability of GH2β ‐glucuronidases via domain reassembly. Biotechnology and Bioengineering. 2021, 118(5): 1962-1972.
7. Jalees ul Hassan, Imdaad Kaleem, Aamir Rasool, Xu Ke, Rana Adnan Tahir, Lv Bo*, Li Chun*. Engineered Saccharomyces cerevisiae for the De Novo Synthesis of the Aroma Compound Longifolene [J]. Chemical Engineering Science, 2020: 115799.
8. Zhang Teng, Liu Hu, Lv Bo*, Li Chun*. Regulating strategies for producing carbohydrate active enzymes by filamentous fungal cell factories[J]. Frontiers in Bioengineering and Biotechnology, 2020, 8.
9. Lv Bo#, Sun Hanli#, Huang Shen, Feng Xudong, Jiang Tao, Li Chun*. Structure-guided engineering of the substrate specificity of a fungal β-glucuronidase toward triterpenoid saponins. Journal of Biological Chemistry,2018, 293(2), 433-443.
10. Liu xiaochen, Zhang Liang, Feng Xudong, Lv Bo*, Li Chun. Biosynthesis of Glycyrrhetinic Acid-3-O-monoglucose Using Glycosyltransferase UGT73C11 from Barbarea vulgaris[J]. Industrial & Engineering Chemistry Research, 2017, 56(51): 14949-14958.
11. Xu Ke, Yu Liping, Bai Wenxin, Xiao Bing, Liu Yueqin, Lv Bo*, Li Jun* , Li Chun. Construction of thermo-tolerant yeast based on an artificial protein quality control system (APQC) to improve the production of bio-ethanol. Chemical Engineering Science, 2018, 177: 410-416.
12 Zhang Teng, Liu Hu, Lv Bo*, Li Chun*. Regulating strategies for producing carbohydrate active enzymes by filamentous fungal cell factories[J]. Frontiers in Bioengineering and Biotechnology, 2020, 8.
13 Xu Ke#, Lv Bo#, Huo Yi-Xin*, Li Chun*. Toward the lowest energy consumption and emission in biofuel production: combination of ideal reactors and robust hosts. Current Opinion in Biotechnology, 2018, 50: 19-24.
14 Sun, Wentao, Xue Haijie, liu Hu, Lv Bo, Yu Yang, Wang Ying, Li Chun. Controlling Chemo- and Regio-selectivity of a plant P450 in yeast cell towards rare licorice triterpenoids Biosynthesis. The ACS Catalysis. 2020 doi: 10.1021 / acscatal. 0 c00128 < br > 15 Liu Hu, Cao Mingming, Wang Ying, Lv Bo, & Li Chun. Bioengineering oligomerization and monomerization of enzymes: learning from natural evolution to matching the demands for industrial applications. Critical Reviews in Biotechnology, 2020:1-16.
16 Xu Yinghua, Feng Xudong, Jia Jintong, Chen Xinyi, Jiang Tian, Rasool Aamir, Lv Bo, Qu Liangti, Li Chun*. A Novel β-Glucuronidase from Talaromyces pinophilus LI-93 Precisely Hydrolyzes Glycyrrhizin into Glycyrrhetinic Acid 3-O-Mono-β-d-Glucuronide. Applied and Environmental Microbiology, 2018,84(19):00755-18