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Research Interests
At present, the main research direction of our research group is the regulation of RNA-mediated gene expression in bacteria, especially the regulation mechanism of pathogenic gene expression. The molecular mechanism of gene expression regulation at the RNA level was elucidate by means of biochemistry, structural biology and microbiology, providing theoretical basis and new ideas for the treatment of related diseases.
At present, the main research direction of our research group is the regulation of RNA-mediated gene expression in bacteria, especially the regulation mechanism of pathogenic gene expression. The molecular mechanism of gene expression regulation at the RNA level was elucidate by means of biochemistry, structural biology and microbiology, providing theoretical basis and new ideas for the treatment of related diseases.
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Dynamic control of bacterial antiphage defense through the CdnG–Cap5 cyclic oligonucleotide–based antiphage pathway in Vibrio cholerae
Ye, F., Gong, J., Ge, Y., Li, Z., Yin, S., Gao, A. & Zhu, Y., Jan 2026, In: Journal of Biological Chemistry. 302, 1, 111021.Research output: Contribution to journal › Article › peer-review
Open Access -
Bacterial restriction-modification systems: mechanisms of defense against phage infection
Kang, H., Gao, A. & Zhu, Y., Oct 2025, In: Biophysics Reports. 11, 5, p. 330-343 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access2 Link opens in a new tab Citations (Scopus) -
Development of conformation-selective antibodies targeting human SLC15A4
Zhu, Y., Zhang, X., Zhang, Q., Sun, P., Liu, K., Nie, X., Ma, J., Zhang, L., Gao, Y., Wang, Y., Liu, S., Gao, A., Zhang, L. & Gao, P., Dec 2025, In: Nature Communications. 16, 1, 7324.Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular basis of SLC19A1-mediated folate and cyclic dinucleotide transport
Zhang, Q., Zhang, X., Liu, K., Zhu, Y., Nie, X., Ma, J., Sun, P., Li, Z., Gao, Y., Liu, S., Gao, A., Zhang, L. & Gao, P., Dec 2025, In: Nature Communications. 16, 1, 3146.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Citations (Scopus) -
Substrate recognition diversity and transport dynamics of ABCC1
Sun, P., Liu, K., Zhang, L., Zhang, Q., Gao, Y., Li, Z., Zhu, Y., Liu, S., Zhang, L., Gao, A. & Gao, P., Dec 2025, In: Nature Communications. 16, 1, 10499.Research output: Contribution to journal › Article › peer-review
Open Access