The early diagnosis of alzheimer's disease: From behavioral to genetic study

Yanna Ren*, Weiping Yang, Xiaoyu Tang, Fengxia Wu, Satoshi Takahashi, Jinglong Wu

*此作品的通讯作者

科研成果: 书/报告/会议事项章节章节同行评审

1 引用 (Scopus)

摘要

Alzheimer's disease, a common form of dementia, is a type of neurodegenerative disease that affects more than 30% of the population older than 85. Clinically, it is characterized as memory loss and cognitive decline. Pathologically, its symptoms include cerebral atrophy, amyloid plaques and NFTs. Generally, the life expectancy is no more than nine years after the definite diagnosis, and life expectancy exceeds 14 years in only 3% of patients. Presently, there is no effective treatment to stop the process; the only measures we can take are to ease or improve symptoms temporarily. Therefore, it is necessary to diagnosis the disease in the early stage, such as through imaging detection via CT, MRI, PET and MSR, or prediction before the disease (genetic examination). However, literature data have supported the notion that Alzheimer's disease patients show cognitive reserve abilities to some degree. In the future, research perspectives may focus on the cognitive training paradigms in compensatory and restorative strategies.

源语言英语
主期刊名Improving the Quality of Life for Dementia Patients through Progressive Detection, Treatment, and Care
出版商IGI Global
1-16
页数16
ISBN(电子版)9781522509264
ISBN(印刷版)1522509259, 9781522509257
DOI
出版状态已出版 - 11 10月 2016
已对外发布

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