TY - CHAP
T1 - The early diagnosis of alzheimer's disease
T2 - From behavioral to genetic study
AU - Ren, Yanna
AU - Yang, Weiping
AU - Tang, Xiaoyu
AU - Wu, Fengxia
AU - Takahashi, Satoshi
AU - Wu, Jinglong
N1 - Publisher Copyright:
© 2017, IGI Global.
PY - 2016/10/11
Y1 - 2016/10/11
N2 - Alzheimer's disease, a common form of dementia, is a type of neurodegenerative disease that affects more than 30% of the population older than 85. Clinically, it is characterized as memory loss and cognitive decline. Pathologically, its symptoms include cerebral atrophy, amyloid plaques and NFTs. Generally, the life expectancy is no more than nine years after the definite diagnosis, and life expectancy exceeds 14 years in only 3% of patients. Presently, there is no effective treatment to stop the process; the only measures we can take are to ease or improve symptoms temporarily. Therefore, it is necessary to diagnosis the disease in the early stage, such as through imaging detection via CT, MRI, PET and MSR, or prediction before the disease (genetic examination). However, literature data have supported the notion that Alzheimer's disease patients show cognitive reserve abilities to some degree. In the future, research perspectives may focus on the cognitive training paradigms in compensatory and restorative strategies.
AB - Alzheimer's disease, a common form of dementia, is a type of neurodegenerative disease that affects more than 30% of the population older than 85. Clinically, it is characterized as memory loss and cognitive decline. Pathologically, its symptoms include cerebral atrophy, amyloid plaques and NFTs. Generally, the life expectancy is no more than nine years after the definite diagnosis, and life expectancy exceeds 14 years in only 3% of patients. Presently, there is no effective treatment to stop the process; the only measures we can take are to ease or improve symptoms temporarily. Therefore, it is necessary to diagnosis the disease in the early stage, such as through imaging detection via CT, MRI, PET and MSR, or prediction before the disease (genetic examination). However, literature data have supported the notion that Alzheimer's disease patients show cognitive reserve abilities to some degree. In the future, research perspectives may focus on the cognitive training paradigms in compensatory and restorative strategies.
UR - http://www.scopus.com/inward/record.url?scp=85015577501&partnerID=8YFLogxK
U2 - 10.4018/978-1-5225-0925-7.ch001
DO - 10.4018/978-1-5225-0925-7.ch001
M3 - Chapter
AN - SCOPUS:85015577501
SN - 1522509259
SN - 9781522509257
SP - 1
EP - 16
BT - Improving the Quality of Life for Dementia Patients through Progressive Detection, Treatment, and Care
PB - IGI Global
ER -