Diagnosing Parkinson’s Disease Using Multimodal Physiological Signals

Guoxin Guo, Shujie Wang, Shuaibin Wang, Zhiyu Zhou, Guangying Pei*, Tianyi Yan

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

7 Citations (Scopus)

Abstract

Parkinson’s disease (PD) is the second most common neurodegenerative disease after Alzheimer’s disease. Due to the complex etiology and diverse clinical symptoms, it’s difficult to accurately diagnose PD. In this study, we applied multimodal physiological signals, which include electroencephalography (EEG), electrocardiogram (ECG), photoplethysmography (PPG), and respiratory (RA), to classify PD and healthy control (HC) based on a multimodal support vector machine (SVM). Our experiments achieved an accuracy of 96.03%. Besides, we performed statistical analysis on the four types of physiological data of the PD group and the HC group. Results showed that the EEG of non-dementia PD patients had a significant decrease in high-frequency power, and the high-frequency energy distribution of the normalized PPG signal increased compared with HC. The current study suggests that combining the physiological information of multiple models and machine learning methods could improve the diagnosis accuracy of PD disease and be a potentially effective method of clinical diagnosis.

Original languageEnglish
Title of host publicationHuman Brain and Artificial Intelligence - Second International Workshop, HBAI 2020, Held in Conjunction with IJCAI-PRICAI 2020, Revised Selected Papers
EditorsYueming Wang
PublisherSpringer Science and Business Media Deutschland GmbH
Pages125-136
Number of pages12
ISBN (Print)9789811612879
DOIs
Publication statusPublished - 2021
Event2nd International Workshop on Human Brain and Artificial Intelligence, HBAI 2020 held in Conjunction with IJCAI-PRICAI 2020 - Yokohama, Japan
Duration: 7 Jan 20217 Jan 2021

Publication series

NameCommunications in Computer and Information Science
Volume1369 CCIS
ISSN (Print)1865-0929
ISSN (Electronic)1865-0937

Conference

Conference2nd International Workshop on Human Brain and Artificial Intelligence, HBAI 2020 held in Conjunction with IJCAI-PRICAI 2020
Country/TerritoryJapan
CityYokohama
Period7/01/217/01/21

Keywords

  • Electroencephalography
  • Machine learning
  • Multimodal physiological signals
  • Parkinson’s disease

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