A simple desorption atmospheric pressure chemical ionization method for enhanced non-volatile sample analysis

Md Matiur Rahman; Ting Jiang; Yang Tang; Wei Xu

doi:10.1016/j.aca.2017.11.033

A simple desorption atmospheric pressure chemical ionization method for enhanced non-volatile sample analysis

Md Matiur Rahman, Ting Jiang, Yang Tang, Wei Xu^*

^*Corresponding author for this work

School of Medical and Technology

Beijing Institute of Technology

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

In this work, a simple desorption atmospheric pressure chemical ionization (SDAPCI) source is studied and optimized for analyzing a wide variety of samples such as nonvolatile, volatile and biological samples. In this ion source, the heated mass inlet was used for sample desorption, and a solid needle was used to produce a corona discharge for ionization. The utilization of any additional gas or heater is not required in SDAPCI. Due to its high sensitivity, only a small amount of sample is needed. Sample loading and the consequent mass spectrometry analysis process could be easy and fast, which was demonstrated by the analyses of different types of samples ranging from non-volatile to volatile compounds. High-throughput analysis can be performed by SDAPCI source with minimum or no sample preparation.

Original language	English
Pages (from-to)	62-69
Number of pages	8
Journal	Analytica Chimica Acta
Volume	1002
DOIs	https://doi.org/10.1016/j.aca.2017.11.033
Publication status	Published - 9 Mar 2018

Keywords

Biological sample
Corona discharge
Non-volatile compound

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10.1016/j.aca.2017.11.033

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title = "A simple desorption atmospheric pressure chemical ionization method for enhanced non-volatile sample analysis",

abstract = "In this work, a simple desorption atmospheric pressure chemical ionization (SDAPCI) source is studied and optimized for analyzing a wide variety of samples such as nonvolatile, volatile and biological samples. In this ion source, the heated mass inlet was used for sample desorption, and a solid needle was used to produce a corona discharge for ionization. The utilization of any additional gas or heater is not required in SDAPCI. Due to its high sensitivity, only a small amount of sample is needed. Sample loading and the consequent mass spectrometry analysis process could be easy and fast, which was demonstrated by the analyses of different types of samples ranging from non-volatile to volatile compounds. High-throughput analysis can be performed by SDAPCI source with minimum or no sample preparation.",

keywords = "Biological sample, Corona discharge, Non-volatile compound",

author = "Rahman, {Md Matiur} and Ting Jiang and Yang Tang and Wei Xu",

note = "Publisher Copyright: {\textcopyright} 2017 Elsevier B.V.",

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doi = "10.1016/j.aca.2017.11.033",

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T1 - A simple desorption atmospheric pressure chemical ionization method for enhanced non-volatile sample analysis

AU - Rahman, Md Matiur

AU - Jiang, Ting

AU - Tang, Yang

AU - Xu, Wei

PY - 2018/3/9

Y1 - 2018/3/9

N2 - In this work, a simple desorption atmospheric pressure chemical ionization (SDAPCI) source is studied and optimized for analyzing a wide variety of samples such as nonvolatile, volatile and biological samples. In this ion source, the heated mass inlet was used for sample desorption, and a solid needle was used to produce a corona discharge for ionization. The utilization of any additional gas or heater is not required in SDAPCI. Due to its high sensitivity, only a small amount of sample is needed. Sample loading and the consequent mass spectrometry analysis process could be easy and fast, which was demonstrated by the analyses of different types of samples ranging from non-volatile to volatile compounds. High-throughput analysis can be performed by SDAPCI source with minimum or no sample preparation.

AB - In this work, a simple desorption atmospheric pressure chemical ionization (SDAPCI) source is studied and optimized for analyzing a wide variety of samples such as nonvolatile, volatile and biological samples. In this ion source, the heated mass inlet was used for sample desorption, and a solid needle was used to produce a corona discharge for ionization. The utilization of any additional gas or heater is not required in SDAPCI. Due to its high sensitivity, only a small amount of sample is needed. Sample loading and the consequent mass spectrometry analysis process could be easy and fast, which was demonstrated by the analyses of different types of samples ranging from non-volatile to volatile compounds. High-throughput analysis can be performed by SDAPCI source with minimum or no sample preparation.

KW - Biological sample

KW - Corona discharge

KW - Non-volatile compound

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U2 - 10.1016/j.aca.2017.11.033

DO - 10.1016/j.aca.2017.11.033

M3 - Article

C2 - 29306414

AN - SCOPUS:85035104183

SN - 0003-2670

VL - 1002

SP - 62

EP - 69

JO - Analytica Chimica Acta

JF - Analytica Chimica Acta

ER -

A simple desorption atmospheric pressure chemical ionization method for enhanced non-volatile sample analysis

Abstract

Keywords

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